Blood DNA methylation-predicted plasma protein levels and colorectal cancer survival. [PDF]
Richards AR +13 more
europepmc +1 more source
Clinical Significance of Copper Chaperone for Superoxide Dismutase in Colorectal Cancer
ABSTRACT Background Targeting Cu transport proteins is an innovative therapeutic approach for combating cancer. However, the mechanisms underlying the malignant potential of Cu transport proteins remain largely unknown. To address this issue, we focused on the oncogenic potential of copper chaperones for superoxide dismutase (CCS) in colorectal cancer (
Nobuo Takiguchi +15 more
wiley +1 more source
Comparison of the differentially enriched mutations/pathways between stage II and stage IV dMMR/MSI-H colorectal cancer. [PDF]
Han C +5 more
europepmc +1 more source
This study analyzed 58 503 laparoscopic right hemicolectomies for colon cancer in Japan between 2018 and 2022, comparing outcomes between male and female surgeons. No significant differences were found in surgical mortality or severe complications. Tailored surgical training programs for female surgeons may further enhance surgical outcomes.
Akihisa Matsuda +10 more
wiley +1 more source
Comprehensive Landscape of Diagnostic, Prognostic and Predictive Biomarkers in Colorectal Cancer: From Genomics to Multi-Omics Integration in Precision Medicine. [PDF]
Agüera-Sánchez A +3 more
europepmc +1 more source
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi +9 more
wiley +1 more source
Erratum: Association of <i>RPS20</i> Loss-of-Function Variants With Colorectal Cancer Risk in a Cohort of Over 950,000 Individuals. [PDF]
Herrera-Mullar J +5 more
europepmc +1 more source
In advanced colorectal cancer, tumors with mature tertiary lymphoid structures (TLS) exhibited abundant infiltration of CD3‐ and CD8‐positive lymphocytes in both primary and metastatic sites, indicating an activated immune response. The presence of mature TLS was also associated with favorable chemotherapy sensitivity and improved prognosis.
Nobuhiro Hosoi +9 more
wiley +1 more source
Association of alcohol intake over the lifetime with colorectal adenoma and colorectal cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. [PDF]
O'Connell CP +6 more
europepmc +1 more source

