Results 31 to 40 of about 1,107,300 (284)

A learning community approach to identifying interventions in health systems to reduce colorectal cancer screening disparities. [PDF]

, 2018
Although colorectal cancer (CRC) screening in the United States has been increasing, screening rates are not optimal, and there are persistent disparities in CRC screening and mortality, particularly among minority patients.
DiCarlo, Melissa, Fleisher, Linda, Lambert, Emily, Man, Lillian C., Myers, Ronald, Romney, Martha, Sifri, Randa   +6 more
core   +2 more sources

Serum Long-Noncoding RNA H19 and β-Catenin as Biomarkers for Early Diagnosis of Colorectal Cancer in Egyptian Patients: A Case Control Study

Journal of Coloproctology, 2022
Colorectal cancer (CRC) is the third most prevalent cancer and the second most common cause of cancer death; however, its early detection can improve the survival. Colonic polyps are considered one of the CRC's major risk factors.
Ayat Abdelrahman Abdelrahman Elshazly, Mohammed Nageeb Desouky, Iman Hassan Diab, Abeer Mahmoud Ali Ibrahim, Fatma Ibrahim Dwedar   +4 more
doaj   +1 more source

Pharmacoproteomic characterisation of human colon and rectal cancer [PDF]

, 2017
Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models for proteome-guided pre-clinical drug sensitivity studies are only beginning to emerge.
Domingo, Enric, Feller, Stephan M, Frejno, Martin, Heinzlmeir, Stephanie, Jarzab, Anna, Jesinghaus, Moritz, Johnstone, Elaine, Kerr, David, Klaeger, Susan, Knapp, Stefan, Koch, Heiner, Kramer, Karl, Kuster, Bernhard, Meng, Chen, Ruprecht, Benjamin, Slotta-Huspenina, Julia, Weichert, Wilko, Wilhelm, Mathias, Zenezini Chiozzi, Riccardo, Zheng, Runsheng   +19 more
core   +1 more source

Promotion and provision of colorectal cancer screening: a comparison of colorectal cancer control program grantees and nongrantees, 2011-2012. [PDF]

, 2014
IntroductionSince 2009, the Centers for Disease Control and Prevention (CDC) has awarded nearly $95 million to 29 states and tribes through the Colorectal Cancer Control Program (CRCCP) to fund 2 program components: 1) providing colorectal cancer (CRC ...
DeGroff, Amy, Escoffery, Cam, Hannon, Peggy A, Kohn, Marlana, Maxwell, Annette E, Vernon, Sally W, Vu, Thuy   +6 more
core   +2 more sources

Lidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer

Cancer Management and Research, 2020
Juan Du,* Liying Zhang,* Hongzhong Ma, Yang Wang, Pengpeng Wang Department of Anesthesiology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, Shandong, People’s Republic of China*These authors contributed equally to
Du J, Zhang L, Ma H, Wang Y, Wang P
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Functional Effects of let-7g Expression in Colon Cancer Metastasis. [PDF]

, 2019
MicroRNA regulation is crucial for gene expression and cell functions. It has been linked to tumorigenesis, development and metastasis in colorectal cancer (CRC).
Chang, Che-Mai, Chang, Wei-Chiao, Chen, Ben-Kuen, Chiu, Siou-Jin, Hsu, Wen-Li, Huang, Chien-Yu, Maio, Zhi-Feng, Tsai, Yao-Ting, Wan, Yu-Jui Yvonne, Wang, Jaw-Yuan, Wong, Henry Sung-Ching   +10 more
core  

Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test

Autoimmunity, 2019
Study objectives: Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was observed in Sweden following mass-vaccination with Pandemrix®.
Madeleine Wallenius, Alexander Lind, Omar Akel, Emma Karlsson, Markus Svensson, Elin Arvidsson, Anita Ramelius, Carina Törn, Lars Palm, Åke Lernmark, Helena Elding Larsson   +10 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Convolutional-Code-Specific CRC Code Design

, 2015
Cyclic redundancy check (CRC) codes check if a codeword is correctly received. This paper presents an algorithm to design CRC codes that are optimized for the code-specific error behavior of a specified feedforward convolutional code.
Daneshrad, Babak, Lou, Chung-Yu, Wesel, Richard D.   +2 more
core   +1 more source