Results 31 to 40 of about 174,118 (259)
HSPA4 Knockdown Retarded Progression and Development of Colorectal Cancer
Cancer Management and Research, 2021 Mingliang Zhang,* Weigang Dai,* Zhanyu Li, Liang Tang, Jianhui Chen, Chuangqi Chen Department of Colorectal Surgery, Gastrointestinal Surgery Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, Guangdong Province, People ...
Zhang M +5 more
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FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Cancer Management and Research, 2021 Wang Y, Wang H, Zhang J, et al. Cancer Manag Res. 2020;12:8465–8479.The Editor-in-Chief and Publisher of Cancer Management and Research wish to retract the published article.The journal was notified of potential data errors in the ...
Wang Y +7 more
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Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Cancer Management and Research, 2019 Juan Ye,1–3,* Qiu-yun Luo,1,* Xue-ping Wang,4 Zhen-yi Liu,5 Mei-xian Chen,6 Hao Huang,7 Lin Zhang1,4 1Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-
Ye J +6 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Australian Biosecurity CRC for Emerging Infectious Diseases (AB-CRC) [PDF]
Microbiology Australia, 2003 The Australian Biosecurity Cooperative Research Centre for Emerging Infectious Disease (AB-CRC) was a successful applicant under the Federal Government?s 2002 CRC programme, and will be formally established from July 2003. The aim of the AB-CRC is to protect Australia?s health, livestock, wildlife and economic resources by developing new capabilities ...
John S Mackenzie, Lisa Adams
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine +40 more
wiley +1 more source
Open Life SciencesColorectal cancer (CRC) is the third most common tumor, with an increasing number of deaths worldwide each year. Tremendous advances in the diagnosis and treatment of CRC have significantly improved the outcomes for CRC patients.
Liu Jiaojiao, Liu Yanchao, Zhao Qi
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