Results 201 to 210 of about 943,536 (329)

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Cell Type-Specific Encoding of Cocaine-Conditioned Responses in the Lateral Preoptic Area. [PDF]

Eur J Neurosci
Mejaes JI, Rajendran R, Sayed K, Yecham P, Bernstein A, Barker DJ.   +5 more
europepmc   +1 more source

Cre driver lines to target the NE system in mice.

Chantal Wissing (21673310), Lena S. Eschholz (21673313), Maxime Maheu (3604928), Kathrin Sauter (21673316), Fabio Morellini (10515020), J. Simon Wiegert (10515023), Alexander Dieter (10515011)   +6 more
openalex   +1 more source

Investigation of Oxtr-expressing Neurons Projecting to Nucleus Accumbens using Oxtr-ires-Cre Knock-in prairie Voles (Microtus ochrogaster)

, 2020
Kengo Horie, Kiyoshi Inoue, Katsuhiko Nishimori, Larry J. Young   +3 more
openalex   +1 more source

Inter‐chromosomal recombination of Mll and Af9 genes mediated by cre‐ loxP in mouse development [PDF]

, 2000
Emma C Collins, Richard Pannell, Elizabeth M. Simpson, A. Förster, Terence H. Rabbitts   +4 more
openalex   +1 more source

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

Advanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang, Xiao Li, Shuyue Lei, Qingqing Li, Yi Zhang, Zhizhen Hui, Jinjin Ren, Xuelian Yang, Xiaoqian Yang, Chunlan Feng, Yousheng Xu, Dongxin Zhao, Wei Tang   +12 more
wiley   +1 more source

Seurat Cell cycle analysis shows similar distribution of cells in G1, G2M, and S phases between Myrf^fl/fl and Rx > cre Myrf^fl/fl.

Michelle L. Brinkmeier (18709048), Su Qing Wang (21094583), Hannah A. Pittman (21094586), Leonard Y. Cheung (21094589), Lev Prasov (243235)   +4 more
openalex   +1 more source

Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti [PDF]

, 2017
Irina Häcker, Robert A. Harrell, Gerrit Eichner, Kristina L. Pilitt, David A. O’Brochta, Alfred M. Handler, Marc F. Schetelig   +6 more
openalex   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Identification of DARPP-32 as a novel sleep regulator in physiological conditions and experimental Parkinsonism. [PDF]

iScience
Pisanò CA, Santino ML, Russotto A, Fisone G.   +3 more
europepmc   +1 more source