Results 211 to 220 of about 943,536 (329)

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Hidden Toll of CRE Colonization: Tripled Three-Year Mortality Risk and Increased Bloodstream Infection Burden After Allo-HSCT-A Propensity-Adjusted Study. [PDF]

Infect Drug Resist
Zhang Y, Wang R, Lyu G, Wang L, Liu X, Tian L, Huang Y, Kou J, Wu S, Cao W.   +9 more
europepmc   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Epidemiological Characteristics and Carbapenemase Analysis of Carbapenem-Resistant Enterobacterales Isolates in a Teaching Hospital in Guangzhou, China

Infection and Drug Resistance
Yiwen Li,* Ying Mai,* Yingxin Liu,* Yueting Jiang Department of Clinical Laboratory, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, National Center for ...
Li Y, Mai Y, Liu Y, Jiang Y
doaj  

Large neutral amino acid uptake and mTOR activation within CD4 T cells coordinate type 2 immunity and host resistance to <i>Trichuris muris</i>. [PDF]

Discov Immunol
Krauss MZ, Hayes KS, Hodge SH, Villegas-Mendez A, Hepworth MR, Sinclair LV, Couper KN, Grencis RK.   +7 more
europepmc   +1 more source

Targeting Tmem63b and Piezo2 in C-fiber low threshold mechanoreceptor: limitation of Vglut3 -IRES- Cre [PDF]

Daniel J. Orlin, Antonio de Arriba Muñoz, Sage Berryman, Destinee Semidey, Swetha E. Murthy   +4 more
openalex   +1 more source

Review for "Characterization and manipulation of Corticothalamic neurons in associative cortices using Syt6‐Cre transgenic mice"

, 2021
Francisco Clascá
openalex   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Phosphorylations of serines 21/9 in glycogen synthase kinase 3α/β are dispensable for V600EBRAF-driven premalignant tumour development in the mouse intestine. [PDF]

PLoS One
Farahmand P, Rzasa P, Green C, Hey F, Giblett S, Jin H, West K, Sylvius NB, Pritchard CA, Rufini A.   +9 more
europepmc   +1 more source

The concealed difficulties of aligning CRE decisions to corporate goals [PDF]

, 2006
Marcello Tonelli
openalex