Results 111 to 120 of about 102,139 (259)

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Rhabdomyolysis presenting as abdominal pain: importance of early creatine kinase testing. [PDF]

Ann Med Surg (Lond)
Khatri PK, Sharma D, Gautam K.
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Creatine kinase imaging (CKI) for in vivo whole-brain mapping of creatine kinase reaction kinetics. [PDF]

Proc Natl Acad Sci U S A
Widmaier M, Kaiser A, Pandurevic P, Lim SI, Döring A, Huang Z, Wenz D, Xiao Y, Jiang Y, Lin Y, Xin L.   +10 more
europepmc   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

Health check revealed elevation of creatine kinase related to hypothyroidism. [PDF]

Endocrinol Diabetes Metab Case Rep
Luo X, Quan Y, Luo G.
europepmc   +1 more source

Serum Apelin‐13 and Galectin‐3 in COVID‐19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case–Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Serum Apelin‐13 and Galectin‐3 levels were measured by ELISA in COVID‐19–positive patients and controls and evaluated alongside routine biochemical parameters. COVID‐19 patients showed significant alterations in liver, renal, inflammatory, and metabolic markers.
İsmail Uğurlu
wiley   +1 more source

Prognostic role of creatine kinase-MB in elderly patients with sepsis. [PDF]

Eur J Med Res
Li J, Wang Q, Che S, Wang Z, Chen S, Wang S, Wei X.   +6 more
europepmc   +1 more source

Early prediction of acute kidney injury in traumatic and non‐traumatic rhabdomyolysis using an interpretable machine learning model: A multicenter study with external validation

Journal of Intelligent Medicine, EarlyView.
Abstract Acute kidney injury (AKI) is a common and severe complication of rhabdomyolysis (RM), and early risk stratification remains challenging because of its multifactorial and heterogeneous nature. We developed and externally validated an interpretable machine learning (ML) model for early prediction of AKI in RM across traumatic and non‐traumatic ...
Chunli Liu, Jie Shi, Fengjuan Wang, Liang Ma, Huangang Hu, Li Zhang, Jie Song, Heng Jin, Dingwei Yang, Xiaoqin Guo, Haojun Fan, Qi Lv   +11 more
wiley   +1 more source

When a Seizure Is Not Just a Seizure: Rhabdomyolysis and Acute Kidney Injury as a Reminder to Check Creatine Kinase. [PDF]

Cureus
Alsherbeeny AS, Rahman L, Soliman LT, Anwar H.   +3 more
europepmc   +1 more source