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Creatine, Creatine Kinase, and Aging

Sub-cellular biochemistry, 2018
With an ever aging population, identifying interventions that can alleviate age-related functional declines has become increasingly important. Dietary supplements have taken center stage based on various health claims and have become a multi-million dollar business.
Ritu A. Shetty   +2 more
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Creatine Kinase

CRC Critical Reviews in Clinical Laboratory Sciences, 1982
Creatine kinase is present in significant concentrations in skeletal muscle and cardiac muscle and to a lesser extent in gastrointestinal tract and brain tissue. The enzyme has been purified from a variety of tissues and an examination of its kinetic and physical properties reveal that the enzyme consists of two subunits and can exist as three ...
R, Bais, J B, Edwards
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Creatine kinase isoenzymes

Journal of Chromatography B: Biomedical Sciences and Applications, 1988
Analytical methods for and the clinical significance of ATP:creatine-N-phosphotransferase (EC 2.7.3.2, CK) isoenzymes have been described. The main assay methods for the isoenzymes are electrophoresis, ion-exchange chromatography and immunoinhibition.
Tohru Okigaki, Fusae Kanemitsu
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Creatine Kinase Revisited

Journal of Clinical Neuromuscular Disease, 2001
Creatine kinase (CK) is the single most important biochemical test in the evaluation of patients with myopathies. In health, serum CK concentration is higher in men, blacks, muscular individuals, and athletes. Idiopathic hyperCKemia is an entity restricted to asymptomatic patients with a negative family history for a neuromuscular disease acid normal ...
B Katiriji, M M Al Jaberi
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Evolution of Creatine Kinase

Nature, 1967
Comparison of the electrophoretic patterns of creatine kinase in different birds throws some light on the type of evolutionary changes which have affected the multiple forms of this enzyme.
Nathan O. Kaplan   +2 more
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Creatine Kinase Isoenzymes

Clinics in Laboratory Medicine, 1986
Creatine kinase (CK), a widely distributed enzyme in the body, has its highest activities in skeletal muscle and myocardium; when serum CK activities are abnormally increased, injury to these organs must be part of the differential diagnosis. The isoenzyme CK-MB is the most important biochemical test in the diagnosis of acute myocardial infarction.
John A. Lott, Lenox B. Abbott
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Macro‐creatine kinase: a neglected cause of elevated creatine kinase

Internal Medicine Journal, 2015
AbstractMacro‐creatine kinase (macro‐CK) is a neglected cause of raised CK. Over a 10‐year period, we observed five cases. Three patients had macro‐CK type 1. One patient with fibromyalgia underwent several explorations to find a muscular pathology; another, who had elevated CK‐MB (muscle–brain fraction) activity, was referred to a cardiologist, and ...
S. Cecchetti   +4 more
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