Results 371 to 380 of about 1,019,575 (429)

Creatine and creatinine metabolism.

Physiological Reviews, 2000
The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the ...
M. Wyss, R. Kaddurah-Daouk
semanticscholar   +1 more source

Elevated Creatine Kinase and Malignancy

Hospital Practice, 1990
Increased serum levels of CK isoenzymes variously signal heart, brain, or skeletal muscle damage. They may also be markers for advanced tumors with poor prognosis.
Alan E. Skolnick, Charis Eng, Steven E. Come   +2 more
openaire   +3 more sources

How to use: creatine kinase

Archives of disease in childhood - Education & practice edition, 2019
Creatine kinase (CK) remains an essential tool for assessment of muscular weakness and pain in children despite the advent of advanced diagnostic tests in this field. It is also useful in diagnosing and monitoring various other conditions. This article will explore the physiology of CK and clinical situations where the estimation of CK can help the ...
Tanmoy Chakrabarty, Andrew Thompson, Sandya Tirupathi   +2 more
openaire   +3 more sources

Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function

Nature Cell Biology, 2023
Ke Wu, Meisi Yan, Tong Liu, Zhenghai Wang, Yuran Duan, Yan Xia, Guimei Ji, Yuling Shen, Lei Wang, Lin Li, Peixiang Zheng, Bofei Dong, Qingang Wu, Liwei Xiao, Xueying Yang, H.-M. Shen, T. Wen, Jingjing Zhang, Jinfeng Yi, Yuhan Deng, Xu Qian, Leina Ma, Jing Fang, Qingxin Zhou, Zhimin Lu, Daqian Xu   +25 more
semanticscholar   +1 more source

Serum creatine kinase in malnutrition

The Journal of Pediatrics, 1968
Creatine kinase activity in untreated kwashiorkor was found to be low and to rise slowly with treatment. In severely wasted children with kwashiorkor and in children with marasmus, normal activities were sometimes found. In these children creatine kinase activity frequently fell during the first week of treatment before rising again slowly.
Ingrid H. E. Rutishauser, Susan E. Balmer   +1 more
openaire   +3 more sources

Creatine Kinase Isoenzymes

1981
The isolation of CK isoenzymes in pure form from human muscle and brain was first described by Keutel et al. [360]. Recently the preparation of CK isoenzymes from myocardium and brain was described by Carlson et al. [100], Roberts etal. [659] and Lee etal. [431].
H. D. Orth, W. Gerok, B. Webber, H. E. Blum, Bruno Deus   +4 more
openaire   +4 more sources

Hybridization of matrix-bound MM-creatine kinase with BB-creatine kinase and arginine kinase

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1994
Dimeric rabbit muscle creatine kinase (MM-CK) was bound to CNBr-activated Sepharose 4B by one of its subunits (MM-CKA). Treatment of MM-CKA with guanidine hydrochloride released the unbound subunit to yield the matrix-bound monomer (M-CKB). M-CKB recombined with dissociated MM-CK soluble subunits to reconstitute a matrix-bound dimer (MM-CKC).
S. Raghupathi Rami Reddy, David C. Watts
openaire   +3 more sources

Radioimmunoassay for Creatine Kinase Isoenzymes

Science, 1976
Creatine kinase has three isoenzymes designated MM, MB, and BB, with BB being the brain form and MM the muscle form. Antibodies to BB creatine kinase were obtained by immunization of rabbits with human BB creatine kinase. The antibodies demonstrated specificity for BB and MB creatine kinase (myocardial isoenzyme), but no cross-reactivity with MM ...
Charles W. Parker, Burton E. Sobel, Robert Roberts   +2 more
openaire   +3 more sources

Regulation of heart creatine kinase

1987
Magnetization transfer nuclear magnetic resonance (NMR) provides measurement of the velocity of the creatine kinase reaction in the intact heart. Standard one-pulse NMR spectroscopy coupled with conventional biochemical analyses provides information about the average cytosolic concentrations of ATP, creatine phosphate (CrP), creatine (Cr) and H+ in the
Joanne S. Ingwall, John A. Bittl
openaire   +3 more sources

Creatine Kinase Elevations with Clozapine

British Journal of Psychiatry, 1994
We describe a patient with marked elevations of creatine kinase following institution of clozapine treatment. The enzyme levels promptly subsided with discontinuation of clozapine. The clinical features did not meet any of the published criteria for neuroleptic malignant syndrome.
J Stecker, Matcheri S. Keshavan, R K Kambhampati   +2 more
openaire   +3 more sources