Results 171 to 180 of about 867,384 (315)

Development and validation of computable Phenotype to Identify and Characterize Kidney Health in Adult Hospitalized Patients [PDF]

arXiv, 2019
Background: Acute kidney injury (AKI) is a common complication in hospitalized patients and a common cause for chronic kidney disease (CKD) and increased hospital cost and mortality. By timely detection of AKI and AKI progression, effective preventive or therapeutic measures could be offered.
arxiv  

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

Advanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang, Fangzhou Chen, Nier Wu, Lingfei Hu, Haihua Xiao, Hanchen Zhang, Dongsheng Zhou   +6 more
wiley   +1 more source

Renal damage in hypertensive patients attended to at the provincial hospital of Las Tunas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Background: arterial hypertension is one of the most frequent chronic diseases. Its progress time and its adequate management and control are risk factors to cause renal damage.Objective: to determine the presence of renal damage in hypertensive patients
Isora Sánchez Lorenzo, Zadys Leyva Feria, Norge Sánchez Albor   +2 more
doaj  

Elevated Urinary Methylmalonic Acid/creatinine ratio and Serum Sterol levels in Patients with Acute Ischemic Stroke

Romanian Journal of Laboratory Medicine, 2018
Introduction: Sitosterolemia, defined as phytosterolemia, is a rare autosomal recessive disease characterized by elevated blood sterol levels. Our aim was to investigate serum plant sterols, methylmalonic acid, vitamin B12, oxidized-LDL and homocysteine ...
Sivrikaya Abdullah, Ozturk Serefnur, Ekmekci Hakan, Sağlam Aslıhan, Abusoglu Sedat, Unlu Ali   +5 more
doaj   +1 more source

A Real‐Time Cell Death Self‐Reporting Theranostic Agent for Dynamic Optimization of Photodynamic Therapy

Advanced Science, EarlyView.
A cell death self‐reporting photodynamic theranostic nanoagent (CDPN) is developed that integrates photodynamic therapy (PDT) with real‐time K⁺ imaging to provide timely feedback on treatment responses. This approach enables the optimization of the drug‐light interval (DLI), a critical factor in PDT, resulting in significantly enhanced antitumor ...
Wei Bian, Qiyue Wang, Cui He, Pan Tao, Juanjuan Zheng, Yulu Zhang, Jing Li, Fangyuan Li, Hongyan Jia, Daishun Ling   +9 more
wiley   +1 more source

Identifying Sub-Phenotypes of Acute Kidney Injury using Structured and Unstructured Electronic Health Record Data with Memory Networks [PDF]

arXiv, 2019
Acute Kidney Injury (AKI) is a common clinical syndrome characterized by the rapid loss of kidney excretory function, which aggravates the clinical severity of other diseases in a large number of hospitalized patients. Accurate early prediction of AKI can enable in-time interventions and treatments.
arxiv  

Prussian‐Blue Catalysis and NFC Synergy: a Battery‐Free Laser‐Induced Graphene‐Based Platform for Urine Glucose Monitoring at Point‐of‐Care

Advanced Science, EarlyView.
In this study, Merkoçi and his research group present a polymer‐based synthesis to enhance the stability of Prussian blue (PB) nanoparticles. The resulting PB‐infused catalytic hetero‐interface architecture (PB‐CHIA) achieves complete two‐dimensional (2D) and three‐dimensional (3D) substrate coverage (glassy carbon and laser‐induced graphene electrodes)
Sinan Uzunçar, Gabriel Maroli, Massimo Urban, Arben Merkoçi   +3 more
wiley   +1 more source

Prevalence of urolithiasis in Sarawak and associated risk factors: An ultrasonagraphy‐based cross‐sectional study

BJUI Compass, Volume 4, Issue 1, Page 74-80, January 2023., 2023
Abstract Objective The aim of this research is to study the prevalence of urolithiasis among the population of Sarawak Malaysia and the associated risk factors. Patients and Methods A survey was conducted among individuals aged ≥18 years age in three primary health care clinics in the main cities of Sarawak from March 2019 to March 2020.
Kamal Raj Perumal, Richelle Huey Bing Chua, Guan Chou Teh, Clarence Chang Moh Lei   +3 more
wiley   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Feature-Enhanced Machine Learning for All-Cause Mortality Prediction in Healthcare Data [PDF]

arXiv
Accurate patient mortality prediction enables effective risk stratification, leading to personalized treatment plans and improved patient outcomes. However, predicting mortality in healthcare remains a significant challenge, with existing studies often focusing on specific diseases or limited predictor sets. This study evaluates machine learning models
arxiv