Results 181 to 190 of about 1,006,914 (379)

Cardiac troponin T in patients with high creatinine concentration but normal creatine kinase activity in serum [PDF]

, 1996
H Baum, Michael Obst, U Huber, D. Neumeier   +3 more
openalex   +1 more source

CD169+ Macrophage‐Targeted Immunomodulator to Restore Phagocytic Function and Enhance Antigen Presentation for Lymphatic Metastasis Eradication

Advanced Science, EarlyView.
A CD169+ macrophage‐targeted immunomodulator (G‐LNP@S‐D) is developed to co‐deliver a SHP2 inhibitor and STING agonist, thereby restoring phagocytic function, enhancing antigen presentation by CD169+ macrophages, and promoting T cell priming to eradicate lymphatic metastasis.
Xiayun Chen, Lichong Lu, Yibin Liu, Ziqi Liang, Jianqiao Li, Zhouchuan Shao, Youzhi Tang, Jianhua Zou, Shiying Li, Xiaoyuan Chen   +9 more
wiley   +1 more source

A pH‐Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury

Advanced Science, EarlyView.
A biomimetic nanoplatform (CeAst@MK) is engineered for precise therapy of acute kidney injury by integrating cerium‐based antioxidation, natural flavonoid astragalin, and macrophage membrane camouflage. Featuring kidney‐targeted and pH‐responsive release, CeAst@MK scavenges ROS, suppresses inflammation, and restores renal function via modulation of ...
Shichao Zhang, Yuhan Xie, Longchao Zhang, Yuanjiong Qi, Quan Liao, Chenglong Xu, Shushuai Yang, Haiwen Zhou, Qidan Tan, Shiyong Qi   +9 more
wiley   +1 more source

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

Advanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang, Zining Liu, Mengjun Li, Judun Zheng, Ruilin Zhang, Ke Liu, Xiaoxue Li, Shaoying Wen, Jingze Yu, Meijia Pan, Fengbo Ma, Kun Zhou, Zheng Zhao, Chenguang Shen, Yuhui Liao   +14 more
wiley   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

QUANTIFICATION OF PROTEINURIA IN PRE ECLAMPSIA USING PROTEIN AND CREATININE RATIO IN RANDOM URINE SPECIMEN

, 2015
R Padmaja, Mohan Rajeshwari, Swetha Swetha   +2 more
openalex   +1 more source

Exploration for cobalt/nitrogen-doped catalyst to creatinine degradation via peroxymonosulfate activation: Toxicity evaluation, statistical modeling and mechanisms study [PDF]

, 2023
Jiadi Liu, Yawen Dong, Yü Kang, Qian Kong, Kuaibing Wang, Fei‐Fei Mao, Yuanqing Bu, Rong Zhou, Chunyong Zhang, Hua Wu   +9 more
openalex   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Serum Creatinine: Not So Simple!

Nephron, 2017
P. Delanaye, E. Cavalier, H. Pottel
semanticscholar   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source