Results 331 to 340 of about 935,466 (405)

A Comprehensive Model for Separating Systematic Bias and Noise in Metabolomic Timecourse Data—A Nonlinear B‐Spline Mixed‐Effects Approach

open access: yesBiotechnology and Bioengineering, EarlyView.
A nonlinear B‐spline mixed effects model for the simultaneous detection and correction of systematic error in timecourse metabolomics data. Systematic errors–such as those from dilution or incomplete extraction–affect all metabolites similarly and can be corrected by fitting all metabolites together in a single model.
Kathy Sharon Isaac, Stanislav Sokolenko
wiley   +1 more source

Case Report: Something Is Brewing. [PDF]

open access: yesNephrology (Carlton)
Brotherton K, Chacko B.
europepmc   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

open access: yesCancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae   +16 more
wiley   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

open access: yesCancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai   +6 more
wiley   +1 more source

Detection of Fast Decliner of Diabetic Kidney Disease Using Chiral Amino Acid Profiling: A Pilot Study

open access: yesChemistry &Biodiversity, EarlyView.
We examined D‐amino acids in diabetic kidney disease (DKD). Among D‐amino acids, blood D‐serine was identified as a biomarker of DKD, and we found that short‐term change in blood D‐serine showed higher value in fast decliners in DKD patients, which meant the prognostic value of blood D‐serine in DKD.
Yosuke Hirakawa   +7 more
wiley   +1 more source

How to Evaluate Kidney Function in Elite Endurance Athletes: Pros and Cons of Different Creatinine-Based Formulas. [PDF]

open access: yesJ Clin Med
Di Gioia G   +7 more
europepmc   +1 more source

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