Results 41 to 50 of about 657,941 (259)

A cross-sectional and longitudinal cohort study of creatinine-to-cystatin C ratio and cardiovascular disease risk in a middle-aged and elderly population

Frontiers in Endocrinology
BackgroundThe creatinine-to-cystatin C ratio (CCR) has recently been proposed as a proxy indicator for sarcopenia. It has been linked to a range of adverse outcomes. However, the relationship between the CCR and cardiovascular disease (CVD) is not widely
Yuling Chen, Yuling Chen, Fengmin Xu, Jia Li, Yixi Bao   +4 more
doaj   +1 more source

No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study

Antioxidants, 2018
A few cases associating high dose intravenous vitamin C (IVC) administration with renal stone formation have been reported in the literature, however, no long-term studies investigating IVC administration and reported renal stones have been carried out ...
Melissa Prier, Anitra C. Carr, Nicola Baillie   +2 more
doaj   +1 more source

The Effect of Rosuvastatin on Prevention of Contrast-Induced Acute Kidney Injury in Patients with Chronic Kidney Disease

مجله دانشکده پزشکی اصفهان, 2020
Background: Contrast-induced acute kidney injury (CI-AKI) is an important issue in patients who are candidate for using contrast media in order to do diagnostic and therapeutic imagining.
Firouzeh Moeinzadeh, Mohammad-Saleh Jafarpishe, Marzieh Rezaee   +2 more
doaj   +1 more source

Clinical significance of serum neutrophil gelatinase-associated lipocalin in the early diagnosis of renal function deterioration after radical nephrectomy [PDF]

Kosin Medical Journal, 2018
ObjectivesThe standard metrics used to monitor the progression of acute kidney injury (AKI) include markers such as serum creatinine, blood urea nitrogen, and estimated glomerular filtration rate (eGFR).
Taek Sang Kim, Su Hwan Kang, Pil Moon Kang, Hongkoo Ha, Su Dong Kim, Jangho Yoon, Hyunyong Hwang   +6 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Urinary Neutrophil Gelatinase-Associated Lipocalin Level is Associated with the Incidence of Postoperative Acute Kidney Injury: An Observational Study

Bali Journal of Anesthesiology
Background: Acute kidney injury (AKI) remains a significant postoperative complication, often leading to increased morbidity and mortality. Traditional markers, such as serum creatinine, have limitations in early detection.
Pontisomaya Parami, Tjokorda Gde Agung Senapathi, Gede Wirya Kusuma Duarsa, Nyoman Wande, Elysanti Dwi Martadiani, Syafri Kamsul Arif, Steven Okta Chandra, Samuel Dwiputra Widjanarko   +7 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Comparing Cystatin C Estimated GFR With Creatinine Estimated GFR in Acute Kidney Injury Recovery

Kidney International Reports
Introduction: Current guidelines recommend creatinine-based estimated glomerular filtration rate (eGFRcr) to assess kidney recovery after acute kidney injury (AKI); however, this may be inaccurate because of loss of muscle mass.
Kerry L. Horne, Rebecca Packington, John Monaghan, Mary Jo Kurth, Ciaran Richardson, Mark W. Ruddock, Maarten W. Taal, Rosamonde E. Banks, Nicholas M. Selby   +8 more
doaj   +1 more source