Results 191 to 200 of about 410,080 (254)

Comparison of creatinine clearance estimation by three different methods in hypoalbuminaemics

Indian Journal of Urology, 2001
N K Ganesh Prasad, R Prabhakara Rao, V Sivakumar   +2 more
doaj  

Creatinine clearance/eGFR ratio: a simple index for muscle mass related to mortality in ICU patients. [PDF]

BMC Nephrol
Volbeda M, Zijlstra HW, Post A, Kootstra-Ros JE, van der Voort PHJ, Franssen CFM, Nijsten MW.   +6 more
europepmc   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

Long-Term Betaine Supplementation Increases Creatinine Clearance and Upregulates MAS and AT2 Receptor Expression in Spontaneously Hypertensive Rat Kidneys.

Kidney Blood Press Res
Koper M, Jaworska K, Kopacz W, Samborowska E, Ufnal M.   +4 more
europepmc   +1 more source

The Role of Kt/V and Creatinine Clearance on Assisting Optimization of Serum Phosphorus Levels among Patients on Peritoneal Dialysis. [PDF]

Kidney360
Uribarri J, Guedes M, Diaz Bessone MI, Chan L, de la Torre A, Mermelstein A, Garcia-Garcia G, Raimann J, Moraes T, Peters V, Konings C, Farrell D, Sharma S, Guinsburg A, Kotanko P.   +14 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Evaluation of Inflammatory Status in COVID-19 Patients with Chronic Kidney Disease: A Comparative Analysis Based on Creatinine Clearance Levels. [PDF]

Biomedicines
Banta A, Rosca D, Rosca O, Bogdan I, Cerbulescu T, Stana LG, Hogea E, Nistor D.   +7 more
europepmc   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Evaluation of kidney disease using e-GFR compared to measured creatinine clearance. [PDF]

Bioinformation
Pullakanam ST, Krishna B, Madhuri N, Dhas PK, Ramakrishna N.   +4 more
europepmc   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source