Results 51 to 60 of about 775,721 (280)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Why Do Companies Cook the Books? Empirical Study of the Motives of Creative Accounting of Slovak Companies

Administrative Sciences
Studies on creative accounting date back to the latter part of the 20th century. Creative accounting is still a big challenge in financial accounting. The problem of financial statement manipulation might be investigated, for instance, from an accounting,
Jakub Michulek, Lubica Gajanova, Anna Krizanova, Roman Blazek   +3 more
doaj   +1 more source

Developing creative accountants

Revista Catarinense da Ciência Contábil
By addressing innovation, creativity, and problem-solving in corporate contexts, Design Thinking has attracted the interest of both scholars and professionals. Despite this, this methodology has still been little disseminated among accounting professionals.
Wendy Beatriz Witt Haddad Carraro, Letícia Bersch Bruxel, Fernanda da Silva Momo, Alan Bandeira Pinheiro   +3 more
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

PERAN TRANSAKSI PIHAK BERELASI DAN CORPORATE GOVERNANCE TERHADAP CREATIVE ACCOUNTING

Jurnal Akuntansi Multiparadigma
Abstrak - Peran Transaksi Pihak Berelasi dan Corporate Governance terhadap Creative Accounting Tujuan Utama - Riset ini bertujuan mengidentifikasi pengaruh transaksi pihak berelasi, kompensasi, dan tata kelola perusahaaan dalam kecenderungan praktik ...
Zulfatul Nikmah, Dian Perwitasari
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Fool the Markets? Creative Accounting, Fiscal Transparency and Sovereign Risk Premia [PDF]

We investigate the effects of official fiscal data and creative accounting signals on interest rate spreads between bond yields in the European Union. Our model predicts that risk premia contained in government bond spreads should increase in both the ...
Guntram B. Wolff, Kerstin Bernoth
core   +3 more sources

ACCOUNTING ETHICS - RESPONSIBILITY VERSUS CREATIVITY [PDF]

Annals of the University of Petrosani: Economics, 2010
Professional accountants are ordered in some point in their life to take certain decisions that are ethical or not. Accounting ethics is an important aspect of an accountant's work. In the last decades has increased so much interest in accounting ethics so that the financial statements should be prepared to come to include a descriptive report of ...
Valentin Ioan Uşurelu, Mioara Marin (Nedelcu), Alina Elena Danailă (Andrei), Daniela Loghin   +3 more
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Influence of Creative Accounting to the Formation of the Accounting Policy and Accounting’s Results

Buhalterinės Apskaitos Teorija ir Praktika, 2019
The accounting's policy choice and creating is influenced by accounting theory, impact factors, each company's objectives, and this makes company unique.
Diana Bachtijeva
doaj   +1 more source