Results 131 to 140 of about 2,719,145 (307)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Playing Speculative Cat's Cradle
AtlantisInspired by the feminist possibilities within digital technologies and acknowledging their limitations, the authors examine the collaborative process of creating Twine workshops for three conferences, the International Communications Association, the ...
Anna Lee-Popham +5 more
doaj
Exploring children's creative narratives: some theoretical, methodological and applied perscpectives
, 2011 This chapter introduces the edited collection, Exploring Children’s Creative Narratives that offers fresh perspectives on children’s creative narratives and that explores what these perspectives reveal about their imagination, their thought processes and
Coates, Elizabeth, Faulkner, Dorothy
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
RELATIONSHIP BETWEEN STUDENTS’ ABILITY TO ACHIEVE DESIGN TASKS AND CREATIVE THINKING SKILLS
Turkish International Journal of Special Education and Guidance & CounsellingCreative thinking provides students to solve complex problems, through searching for new learning ways in educational activities. This study aimed to reveal higher education students' creative thinking potentials with educational activities.
Kani ÜLGER
doaj
Angels, tooth fairies and ghosts: thinking creatively in an early years classroom
, 2011 This chapter offers an evaluation and interpretation of the creative thinking and collaboration that took place in a class of five year olds in an English primary school during the academic year 2004–05.
Faulkner, Dorothy
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Creative science in theory and practice
Ideas in Ecology and Evolution, 2011 n ...
Bernard Crespi
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source