Results 91 to 100 of about 2,501,548 (303)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Memoirs of a trainer : The search for a balance between quality and best practice [PDF]
, 2006 The field of research training (for students and supervisors) is becoming more heavily regulated by the Federal Government. At the same time, quality improvement imperatives are requiring staff across the University to have better access to information ...
Mayes, Jenny, Winter, Abigail J.
core +1 more source
An English lecturer, a palliative care practitioner, and an absent poet have a confabulation [PDF]
, 2014 The possibilities for developing the poet Douglas Dunn’s archive (which includes the drafts and manuscripts for his collection Elegies, dealing with the terminal illness and death of the poet’s wife from cancer) for therapeutic benefit are explored by an
Jones, Chris, Macpherson, Catriona
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Creative clusters in Europe: a microdata approach [PDF]
Creative industries are highly concentrated forming clusters. One of the main problems for the identification of clusters of creative industries in Europe is the lack of data, constrained in practice to regions (NUTS 2) and influenced by the ...
Blanca De Miguel Molina +4 more
core
Growing our own - recruiting high quality research students by stealth [PDF]
, 2003 Most design students assume that their education is preparing them for a career in professional practice. Until recently the idea of working as researchers or studying for a research degree was not an option.
Fisher, T., Rust, C.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Activating a Research Context in Art and Design Practice
International Journal for the Scholarship of Teaching and Learning, 2007 Practice-based research in art and design is the focus of postgraduate programmes at many universities. The term is useful when practice constitutes a critical part of the research methodology resulting in a form of research through practice.
Nancy de Freitas
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source