Results 81 to 90 of about 2,501,548 (303)

Developing a Framework for Managing Tacit Knowledge in Research using Knowledge Management Models [PDF]

open access: yes, 2008
This research investigates whether and how selected models from Knowledge Management (KM) can be used to devise a framework for building coherent and rigorous methodologies for research in the creative and practice-led disciplines (CPD).
Imani, Yassaman, Niedderer, Kristina
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The review of a design practice learning project to pilot heightened social responsibility and engagement [PDF]

open access: yes, 2003
This paper describes the review of a design project devised to pilot a student community learning experience at a heightened level of social responsibility.
Hilton, Kevin, Young, Robert
core  

Requirements Engineering as Creative Problem Solving: A Research Agenda for Idea Finding [PDF]

open access: yes, 2010
This vision paper frames requirements engineering as a creative problem solving process. Its purpose is to enable requirements researchers and practitioners to recruit relevant theories, models, techniques and tools from creative problem solving to ...
Jones, S.   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Supporting reflection and creative thinking by carers of older people with dementia [PDF]

open access: yes, 2011
This vision paper frames requirements engineering as a creative problem solving process. Its purpose is to enable requirements researchers and practitioners to recruit relevant theories, models, techniques and tools from creative problem solving to ...
Jones, S.   +6 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Filmmaking Research Continuum

open access: yesAkademisk Kvarter
Exploring aspects of the development of filmmaking research within the Academy over past decades, this article focuses on creative practice-based methods and the establishment of filmmaking as a legitimate research endeavour.
Susan Kerrigan   +2 more
doaj   +1 more source

A digitally supported home-based exercise training program and dietary protein intervention for community dwelling older adults: protocol of the cluster randomised controlled VITAMIN trial

open access: yesBMC Geriatrics, 2018
Background Increased physical activity and dietary protein intake are promising interventions to prevent or treat the age-related decline in physical performance in older adults.
Jantine van den Helder   +8 more
doaj   +1 more source

First make something – principled, creative design as a tool for multi-disciplinary research in clinical engineering [PDF]

open access: yes, 1999
Design provides a set of tools for exploring our world and these can give very different insights from the tools of the natural scientist or social scientist.
Rust, C., Whiteley, G., Wilson, A.
core  

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