Results 191 to 200 of about 151,527 (258)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dance/movement therapy in psychotic disorders and eating disorders: a systematic review. [PDF]

Front Psychiatry
Monaco F, Vignapiano A, Landi S, Panarello E, Malvone R, Pullano I, Fiore G, Iazzolino AM, Steardo L, Sosto G, Corrivetti G.   +10 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The impact of walking on creative thinking: A systematic review and meta-analysis. [PDF]

PLoS One
Thabane A, Arora V, Boilard J, Sutoski A, Parpia S, Calic G, Busse JW, McKechnie T, Staibano P, Phillips M, Reiter-Palmon R, Bhandari M.   +11 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Influence of mentors' innovation support on postgraduates' proactive innovation behavior: the chain-mediating role of innovation efficacy and creative process engagement. [PDF]

Front Psychol
Wei J, Peng H, He Y, Shuai C, Wang A.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

AI anxiety and teacher innovative intentions: a moderated serial mediation model of burnout and creative self-efficacy. [PDF]

Front Psychol
Dong T, Yang Z, Fang Y, Che J, Li L, Kong Y.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Creative Forces^® Creative Arts Café: a theory-based creative performance framework for military-connected populations with traumatic brain injury and posttraumatic stress disorder. [PDF]

Front Psychiatry
Vaudreuil R, Palmer A, Moret N, Freeman EK, Sargent P, Buotte P, Chilton G.   +6 more
europepmc   +1 more source