Results 211 to 220 of about 1,189,319 (366)

CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length

open access: yesAdvanced Science, EarlyView.
This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo   +5 more
wiley   +1 more source

Revealing the Principle of Progressively Enhanced Photocatalytic Reactivity in Dual Single‐Atoms‐Mediated Electronic Interactions Optimization of Cd/Te‐TiO2

open access: yesAdvanced Science, EarlyView.
The incrementally enhanced photocatalytic reactivity is attributed to persistent in situ spontaneous growing of atomically dispersed Cd/Te SAs. Consequently, it mutually elevates the electronic density around Cd/Te SAs and strengthens interactions and binding capacity between occupied d orbitals at Cd/Te SAs and empty p orbits in TS.
Yihang Zhang   +5 more
wiley   +1 more source

Combinational creativity and computational creativity

open access: yes, 2018
Creativity is a significant element of design. However, it can be challenging to produce creative ideas that will be of value to society and worthy of design effort. This thesis explores combinational creativity, which involves unfamiliar combinations of familiar ideas, and implements combinational creativity in computational tools to support design ...
openaire   +4 more sources

A Model of Epigenetic Inheritance Accounts for Unexpected Adaptation to Unforeseen Challenges

open access: yesAdvanced Science, EarlyView.
A general model of inheriting changes that are acquired during the lifetime of individuals demonstrates tremendous benefits to the population, including escape from extinction in changing environments. Contrasting the model with experimental data shows that inheritance of acquired changes enables rapid adaptation to unforeseen challenges, and accounts ...
Dino Osmanović   +2 more
wiley   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

open access: yesAdvanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim   +6 more
wiley   +1 more source

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