Results 21 to 30 of about 5,775 (200)

Muscle Activity Adaptations to Spinal Tissue Creep in the Presence of Muscle Fatigue. [PDF]

PLoS ONE, 2016
The aim of this study was to identify adaptations in muscle activity distribution to spinal tissue creep in presence of muscle fatigue.Twenty-three healthy participants performed a fatigue task before and after 30 minutes of passive spinal tissue ...
Jacques Abboud, François Nougarou, Martin Descarreaux   +2 more
doaj   +1 more source

Modeling of creep-fatigue interaction effects on crack growth at elevated temperatures

MATEC Web of Conferences, 2018
The well-known load frequency effect on creep-fatigue crack growth is explained by the interactions between fatigue and creep loading and is quantified using the concept of plasticity-induced crack closure.
Potirniche Gabriel P.
doaj   +1 more source

Predicting creep-fatigue crack growth rates in Alloy 709 using finite element simulations of plasticity and creep-induced crack closure

MATEC Web of Conferences, 2018
This paper reports on a computational study and experimental validation of creep-fatigue crack growth rates at high temperature in two structural materials.
Ramirez Jose, Potirniche Gabriel P., Pugesek Henry, Shaber Nicholas, Taylor Martin, Stephens Robert, Charit Indrajit   +6 more
doaj   +1 more source

Crack Propagation Mechanisms for Creep Fatigue: A Consolidated Explanation of Fundamental Behaviours from Initiation to Failure

Metals, 2018
Background—Creep-fatigue damage is generally identified as the combined effect of fatigue and creep. This behaviour is macroscopically described by crack growth, wherein fatigue and creep follow different principles.
Dan Liu, Dirk John Pons
doaj   +1 more source

Remaining creep properties and fracture behaviour of P92 steel welded joint under prior low cycle fatigue loading

Journal of Materials Research and Technology, 2020
The alternation of creep properties is unavoidable in welded structures after suffering from cyclic damage, which may lead to the premature failure of power plant units and hard to predict. This work is devoted to clarify the influence of prior low cycle
Wei Zhang, Tianyu Zhang, Xiaowei Wang, Haofeng Chen, Jianming Gong   +4 more
doaj   +1 more source

Characterization of the cyclic softening and remaining creep behaviour of P92 steel weldment

Journal of Materials Research and Technology, 2021
Different micro-regions of weldment are expected to present various cyclic softening behaviours during creep–fatigue interaction (CFI), which has a significant influence on the remaining mechanical properties.
Wei Zhang, Xiaowei Wang, Zitong Kang, Tianyu Zhang, Yong Jiang, Xiancheng Zhang, Jianming Gong   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Damage and hardening evolution characteristics of sandstone under multilevel creep–fatigue loading

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
During the operation of artificial underground structures, the surrounding rock experiences fatigue and creep damage caused by several types of disturbances under long-term constant loading.
Zhang Bichuan, Liang Yunpei, Zou Quanle, Ning Yanhao, Kong Fanjie   +4 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source