Results 171 to 180 of about 16,122 (303)
Annals of Neurology, EarlyView.Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto +12 more
wiley +1 more source
Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
Angewandte Chemie International Edition, EarlyView.Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley +1 more source
Mechanism and Performance Characterization of Dry-Process Asphalt Mixtures Modified with LDPE/EVA/SBS Composite Particles. [PDF]
Nanomaterials (Basel)Yi Z +7 more
europepmc +1 more source
Arthritis &Rheumatology, EarlyView.Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley +1 more source
Rheological and Performance Properties of a Bituminous Binder Modified with Date Kernel Powder. [PDF]
Materials (Basel)İnce CB.
europepmc +1 more source
The development of computational FE system for creep damage analysis of weldment
A Finite Element Analysis (FEA) system was designed for the analysis of creep deformation and damage evolution in weldment. This project essentially consists of three parts which involves 1) transfer programme development, 2) numerical integration ...
Tan, Feng +3 more
core
Arthritis &Rheumatology, EarlyView.Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis +22 more
wiley +1 more source
Performance Control and Mechanism Analysis of DCLR-Based Composite High-Modulus Asphalt Based on Synergistic Modification Effect. [PDF]
Materials (Basel)Xu B, Yu X, Gao A, Bu G, Lu K.
europepmc +1 more source
Arthritis &Rheumatology, EarlyView.Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco +8 more
wiley +1 more source