Discussion: “Long-Time Creep Tests of 18 Cr 8 Ni Steel and 0.35 Per Cent Carbon Steel” (Cross, H. C., and Dahle, F. B., 1936, Trans. ASME, 58, pp. 91–96) [PDF]
, 1936 Roger Stuart Brown
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A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
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Creep Deformation of a Mild Steel under Stepwise Varying Periodic Stresses
, 1958 Toshio NISHIHARA +3 more
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Closure to “Discussion of ‘Correlation of Creep Properties by a Diffusion Analogy’” (1953, ASME J. Appl. Mech., 20, pp. 146–147) [PDF]
, 1953 León Green
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
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Brittle Fracture in Creep Rupture Test of Some Heat-Resisting Steels
, 1959 Masao Kanamori, Teishirô Oda
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Discussion: “Progress Report on Tubular Creep Tests” (Norton, F. H., 1941, Trans. ASME, 63, pp. 735–736) and “Interpretation of Creep Tests on Tubes” (Soderberg, C. R., 1941, Trans. ASME, 63, pp. 737–740) [PDF]
, 1941 Ernest L. Robinson
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