Results 121 to 130 of about 542,843 (395)

Analytical and Numerical Modelling of Creep Deformation of Viscoelastic Thick-Walled Cylinder with Fractional Maxwell Model [PDF]

, 2021
Xiang Ding, Na Chen, Yan Zhang, Fan Zhang   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Creep in fibre-reinforced polymer mat composites [PDF]

, 2007
Tensile creeps have been conducted upon a woven, glass-fibre laminated epoxy composite and a 0/90° cross ply, carbon fibre reinforced epoxy composite. For the laminate loading was aligned with a fibre direction.
Dix, S, Garner, AF, Rees, DWA
core  

Interface-controlled creep in metallic glass composites

, 2017
In this work we present molecular dynamics simulations on the creep behavior of $\rm Cu_{64}Zr_{36}$ metallic glass composites. Surprisingly, all composites exhibit much higher creep rates than the homogeneous glass.
Albe, Karsten, Brink, Tobias, Kalcher, Constanze, Rohrer, Jochen, Stukowski, Alexander   +4 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Creep Resistance and Long-Term Strength of Structural Magnesium Alloys [PDF]

, 2006
В. Г. Ткаченко, I.N. Maksimchuk, P. Yu. Volosevich, N.K. Lashuk, Alon Malka, V.V. Friezel   +5 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Effect of creep in titanium alloy Ti-6Al-4V at elevated temperature on aircraft design and flight test [PDF]

Short-term compressive creep tests were conducted on three titanium alloy Ti-6Al-4V coupons at three different stress levels at a temperature of 714 K (825 F).
Jenkins, J. M.
core   +1 more source

Quantum creep and quantum creep transitions in 1D sine-Gordan chains

, 2003
Discrete sine-Gordon (SG) chains are studied with path-integral molecular dynamics. Chains commensurate with the substrate show the transition from collective quantum creep to pinning at bead masses slightly larger than those predicted from the ...
E. K. Sklyanin, E. K. Sklyanin, Florian R. Krajewski, H. J. Schulz, J. M. Kosterlitz, L. M. Floria, M. H. Müser, Martin H. Müser, P. Hänggi, V. L. Berezinski, Y. I. Frenkel   +10 more
core   +1 more source