Results 121 to 130 of about 99,412 (322)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue. In this context, we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.
Yachen Xie+3 more
doaj
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Anomalous Creep as a Precursor to Failure in Granular Materials [PDF]
Granular materials, composed of discrete solid grains, can be modeled as simple mechanical systems. However, these materials can undergo spontaneous slow deformation, or creep, even under small forces and while in apparent mechanical equilibrium; a phenomenon central to understanding soil mechanics and the behavior of earthquake faults.
arxiv
CREEP OF POLYCRYSTALLINE IRON UNDER SMALL TORSIONAL STRESS AND THE EFFECT OF CARBON UPON THE CREEP
KE TING-SUI, KUNG CHING-PING
openalex +1 more source
Mechanical Properties of Concentrated Hydrogels of Agar-agar. II. Creep under Constant Load in Compression [PDF]
Hiroshi Fujita+2 more
openalex +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source