Results 171 to 180 of about 99,751 (297)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Thermal aging of Gr. 91 steel in supercritical thermal plant and its effect on structural integrity at elevated temperature

Nuclear Engineering and Technology
In this study, the influence of thermal aging on structural integrity is investigated for Gr. 91 steel. A commercial grade Gr. 91 steel is used for the virgin material, and service-exposed Gr.
Min-Gu Won, Si-Hwa Jeong, Nam-Su Huh, Woo-Gon Kim, Hyeong-Yeon Lee   +4 more
doaj  

Grass hay mixed-in creep feed or separately-fed differentially affects digestive development in pre- and post-weaning piglets. [PDF]

J Anim Sci Biotechnol
Yao R, Hulshof TG, van Hees HMJ, Cools A, Merckx M, Maes D, Janssens GPJ.   +6 more
europepmc   +1 more source

Discussion: “Creep Damage in a Cr-Mo-V Steel as Measured by Retained Stress Rupture Properties” (Jones, M. H., Newman, D. P., and Brown, Jr., W. F., 1957, Trans. ASME, 79, pp. 117–125) [PDF]

, 1957
M. J. Manjoine
openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Study on the fractional creep model of roadway filling paste under the coupling effect of pore water pressure and stress

Heliyon
Filling paste in deep roadways is significantly affected by groundwater, especially high pore water pressure, which increases the complexity and variability of the filling paste's mechanical properties.
Hongmiao Lv
doaj  

Negative mixing enthalpy and mixing enthalpy alloying leads to interface and size effects towards superb creep resistance of nickel-based single crystalline superalloys. [PDF]

Natl Sci Rev
Zhao J, Yuan X, Zhao Y, Wang Z, Long H, Mao S, Wang L, Han X, Zhang Z.   +8 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Research on Creep Deformation of Dissimilar FSWed T-Joints Under Different Ultrasonic Vibration Modes: Experiment, Constitutive Model, and Simulation Verification. [PDF]

Materials (Basel)
Ye T, Han Y, Zuo D, Fu H, Feng S, Gao C, Li W.   +6 more
europepmc   +1 more source

RELATIONSHIP BETWEEN SMALL ANGLE DISLOCATION BOUNDARIES AND CREEP Technical Report No. 15

, 1954
Betsy Ancker, T.H. Hazlett, E.R. Parker
openalex   +2 more sources