The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee+16 more
wiley +1 more source
Analytical and empirical correlation between magnetic domain wall creep behavior and fundamental magnetic properties. [PDF]
Kim DY, Hu F, Lee SH, Yang H, Choe SB.
europepmc +1 more source
Second quarterly progress report to Materials Laboratory, Wright Air Development Center, Department of the Air Force, on intermediate temperature creep and rupture behavior of titanium and titanium alloys [PDF]
Jeremy V. Gluck, James W. Freeman
openalex
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source
An investigation of the relationship between microstructure and creep-rupture properties of heat-resistant alloys : sixth progress report. [PDF]
A. P. Coldren, James W. Freeman
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Discussion: “Effect of Surface Condition on Creep of Some Commercial Metals” (Sweetland, E. D., and Parker, E. R., 1953, ASME J. Appl. Mech., 20, pp. 30–32) [PDF]
L. C. Cockel
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Creep, Viscoelasticity and Creep Fracture in Solids [PDF]
Iain Le May, John Gittus
openaire +2 more sources
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Progress report to Materials Laboratory, Wright Air Development Center on effect of prior creep on mechanical properties of aircraft structure metals [PDF]
Jeremy V. Gluck+2 more
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