Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Reciprocal-Space Analysis of Structural Reorganization and Orientational Correlation in a Cellulose Nanofibril Suspension during Constant-Stress Creep. [PDF]
Yamagata Y, Araida M, Otobe S.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Pain Sensitivity Profiles Are Associated With Muscle Biomechanics and Clinical Pain in Persons With Symptomatic Knee Osteoarthritis. [PDF]
Johnson AJ, Murillo BC, Cruz-Almeida Y.
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Research and Simulation Analysis of Life Prediction in Notched Structures of DZ411 Alloy. [PDF]
Liu Y, Wang W, Jiang X, Wei D, Wang Y.
europepmc +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Effect of Filler-to-Binder Ratio on the Rheological and Fatigue Performance of Emulsified Asphalt Mastics. [PDF]
Bi F +6 more
europepmc +1 more source
Effect of Processing Parameters on the Creep Behavior and Integrity of Plasma-Sprayed Thermal Barrier Coatings on Ti-6Al-4V. [PDF]
Rodrigues BC +3 more
europepmc +1 more source

