Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Myotonometry and Muscle Force in Patients with Surgically Treated Tibial Pilon Fracture: A Cross-Sectional Study. [PDF]
Bolovan AD +5 more
europepmc +1 more source
Prediction of Inelastic Behavior and Creep-Fatigue Life of Perforated Plates.
Toshihide IGARI +2 more
openalex +2 more sources
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Acute Effects of Different Muscle Contraction Types on Biomechanical and Viscoelastic Properties of the Biceps Brachii Measured with Myotonometry. [PDF]
Szajkowski S, Pasek J, Cieślar G.
europepmc +1 more source
Creep Rupture Properties of Inconel 617 in Simulated HTR-Helium Atmosphere
Kazuaki Mino +3 more
openalex +2 more sources
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Mechanical and Adhesive Properties of Hydrothermally Treated Bamboo Composites Reinforced with Phenolic Resin: Effect of Impregnation with Silica Nanoparticles. [PDF]
Bessala LFB, Li Y.
europepmc +1 more source
FEM analysis and experiments of creep behavior of Rubber-Modified Epoxy
Seiya Hagihara +3 more
openalex +2 more sources

