Results 1 to 10 of about 2,541 (215)

Creep constitutive model of strain energy density considering the whole process of creep deformation. [PDF]

PLoS One
Aiming at the problem that the traditional creep model is difficult to reflect the characteristics of accelerated creep stage of rock, the influence of stress state on accelerated creep is fully considered, and a constitutive model which can describe viscoplastic creep is established based on strain energy density function.
Li Y.
europepmc   +4 more sources

Creep Properties and Constitutive Model of Salt Rock [PDF]

Advances in Civil Engineering, 2021
Due to the advantages of low porosity, low permeability, high ductility, and excellent capacities for creep and damage self‐healing, salt rock is internationally considered as the ideal medium for underground storage of energy and disposal of radioactive waste.
Qiang Zhang, Zhanping Song, Junbao Wang, Yuwei Zhang, Tong Wang   +4 more
openaire   +3 more sources

Numerical implementation of a constitutive model for soil creep [PDF]

Journal of Mechanics of Materials and Structures, 2005
A differential form of 1-D creep model, proposed by Bjerrum in 1967, which was later modified for transient loading conditions is extended to multi-dimensional (2-D and 3-D) state of stress and strain by incorporating concepts of visco-plasticity (Vermeer et al., 1998).
M. A. K. Madurapperuma, Udeni G. Puswewala   +1 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Shear creep characteristics and constitutive model of limestone

International Journal of Mining Science and Technology, 2016
Abstract The characters of limestone in weak interlayer of a high rocky slope in Xuzhou, China, are studied by shear static test and shear creep test. The results show that limestone specimens have attenuation creep properties and constant rate creep properties, almost have no accelerated creep properties.
Mei Yu, Xianbiao Mao, Xinyu Hu
openaire   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source