Results 51 to 60 of about 14,048,300 (182)

Creep characteristics and model study of composite geomembrane with different film thicknesses

Yantu gongcheng xuebao, 2021
Through 90 days of creep tests, the creep laws of composite geomembrane at different thickness levels are compared and analyzed. The previous typical creep models are classified and compared with the creep test results.
YANG Wu 1, 2, SHI Ke-bin 1, 2, HE Jian-xin 1, 2, LIU Liang 1, 2, YANG Hai-hua 1, 2
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The behavior of structures based on the characteristic strain model of creep [PDF]

, 2011
There has been much work over the past two decades to aid the design and assessment engineer in the selection of a suitable material model of creep for high temperature applications.
Boyle, James
core   +4 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A Viscoplasticity Model for Shale Creep Behavior and Its Application on Fracture Closure and Conductivity

Energies
Hydraulic fracturing is the main means for developing low-permeability shale reservoirs. Whether to produce artificial fractures with sufficient conductivity is an important criterion for hydraulic fracturing evaluation.
Shiyuan Li, Jingya Zhao, Haipeng Guo, Haigang Wang, Muzi Li, Mengjie Li, Jinquan Li, Junwang Fu   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Implementation of a new time-dependent shotcrete constitutive model for 3D tunnel modeling

Results in Engineering
Shotcrete behaviors, including modulus and compressive strength, are highly time-dependent. Moreover, freshly applied shotcrete is subjected to loading immediately after application, making its realistic representation both essential and challenging in ...
Sinodos S. Sefene, Dirk Zapf, Martin Achmus   +2 more
doaj   +1 more source

Creep constitutive law prediction via short-term evaluation using a small size testing method

Energy Reports, 2023
To efficiently assess the mechanical reliability and long-term durability of solid oxide fuel cells (SOFCs) and solid oxide electrolyser cells (SOECs), a suitable creep test method and prediction of the material response is necessary.
Yihui Huang, Moeno Kadowaki, Takanori Nakano, Keigo Kumada, Satoshi Watanabe, Tatsuya Kawada, Kazuhisa Sato   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source