Results 161 to 170 of about 3,719 (283)

Evaluation of ingestive behavior and performance of lambs in two feeding systems (creep feeding x native field)

The present study was carried out with the objective of evaluating the ingestive behavior and performance of lambs raised in different feeding systems (creep feeding x native field) and the final performance of the matrices.
Tâmara , Joziéli Quevedo
core   +1 more source

DESENVOLVIMENTO PONDERAL DE CABRITOS LACTENTES COM ACESSO AO CREEP FEEDING EM DIFERENTES IDADES

, 2012
Objetivou-se com este trabalho avaliar o efeito de diferentes períodos de acesso ao creep feeding sobre o ganho de peso, peso a desmama e condição corporal de cabritos mestiços da raça Bôer.
Atoji, Katia, Borges, Gisele Daiane Silveira, Macedo, Vicente de Paulo, Baiffus, Franciele Silveira Borges   +3 more
core  

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Effect of creep feeding on piglet’s performance and behavior until the nursery phase

, 2019
Com objetivo de avaliar o efeito do creep feeding no desempenho e comportamento de leitões até o final da fase de creche, um total de 63 matrizes e suas leitegadas foram distribuídos em um delineamento fatorial 2×2 com creep feeding (sim ou não) e idade ...
Hernig, Luciana Fiorin
core  

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Características de la canal de corderos lactantes con suplementación en creep feeding y creep grazing

, 2013
The work was developed in Sheep and Goat Production Laboratory of UFPR to evaluate the sucking lambs systems of production in pasture, supplemented in creep feeding or creep grazing.
Costa, Ciniro [UNESP], Ribeiro, Ticiany Maria Dias, Piazzetta, Hugo von Linsingen, Fernades, Maria Angela Machado, Silva, Cláudio José Araujo da, Silva, Marina Gabriela Berchiol da [UNESP], Meirelles, Paulo Roberto de Lima, Monteiro, Alda Lúcia Gomes, Prado, Odilei Rogério   +8 more
core  

Feed intake of the sow and playful creep feeding of piglets influence piglet behaviour and performance before and after weaning. [PDF]

Sci Rep, 2019
Middelkoop A, Costermans N, Kemp B, Bolhuis JE.   +3 more
europepmc   +1 more source