Results 71 to 80 of about 76,634 (311)
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Gardner&Lockman Model (2000) and its Application in Numerical Analysis of Composite Beams [PDF]
, 2006 The paper presents analysis of the stress and deflections changes due to creep in statically determinate composite steel-concrete beam. On the basis of the theory of the viscoelastic body of Arutyunian–Trost-Bažant for determining the redistribution of ...
Partov, D., Kantchev, V.
core +1 more source
Advanced Science, EarlyView.Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang +8 more
wiley +1 more source
3D finite element simulations of reinforced concrete elements exposed to fire [PDF]
, 2017 Fire could dramatically reduce strength of reinforced concrete elements and it is considered one of the major threats for the structural safety of buildings: structural members may even collapse due to intensity and duration of fire.
Ceccato, Ciara, Lale, Erol
core
The Design of a semi-prefabricated LVL-concrete composite floor [PDF]
, 2012 This paper describes the design of a novel semi-prefabricated LVL-concrete composite floor that has been developed in New Zealand. In this solution, the floor units made from LVL joists and plywood are prefabricated in the factory and transported to the ...
Fragiacomo, Massimo, Yeoh, David
core +3 more sources
Efficient Approximation Method for Concrete Creep Compliance Function
Yuanzineng kexue jishuFor concrete, the strain tends to grow when the stress is kept at a constant level. This phenomenon is usually referred to as creep. Creep is an important physical property of concrete.
XIANG Huawei1, 2, , , RONG Hua1, 2, 3, FAN Xinglang2, GENG Yan1, BAI Linhong4
doaj +1 more source
Advanced Science, EarlyView.CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu +13 more
wiley +1 more source
Comparison of Creep Prediction Models for Self-Compacting and Conventional Concrete [PDF]
, 2011 Realistic prediction of concrete creep is of crucial importance for durability and long-term serviceability of concrete structures. To date, research about the behaviour of self-compacting concrete (SCC) members, especially concerning the long-term ...
Aslani, F, Nejadi, S
core
Early age behaviour of concrete supercontainers for radioactive waste disposal [PDF]
, 2009 A
Craeye, Bart +3 more
core +2 more sources
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source