Results 11 to 20 of about 11,949 (227)

Membranous Glomerulonephritis With Crescents [PDF]

Kidney International Reports, 2019
INTRODUCTION: Membranous glomerulonephritis (MGN) is rarely associated with necrotizing and crescentic glomerulonephritis (NCGN). METHODS: We report the clinical and pathologic findings in 15 patients with MGN and NCGN associated with anti-neutrophil cytoplasm antibodies (ANCAs), anti-glomerular basement membrane (GBM), or anti-phospholipase A2 ...
Nikolopoulou, Aikaterini, Huang-Doran, Isabel, McAdoo, Stephen P, Griffith, Megan E, Cook, H Terence, Pusey, Charles D   +5 more
openaire   +6 more sources

Crescentic membranoproliferative glomerulonephritis in HIV infection; a mini-review with case study [PDF]

Journal of Nephropathology, 2022
HIV-related renal diseases have become more evident and easier to treat due to the prolonged survival of patients with HIV infection on antiretroviral therapy (ART). There are multiple factors involved in the pathogenesis of this entity.
Priti Meena, Vinant Bhargava, Devinder Singh Rana, Anil Kumar Bhalla, Ashwani Gupta, Manish Malik, Pallav Gupta   +6 more
doaj   +1 more source

Immune Complex-Mediated Crescentic Glomerulonephritis [PDF]

Journal of Clinical and Diagnostic Research, 2022
Immune complex-mediated Glomerulonephritis (GN) comprises a group of disorders including Immunoglobulin A (IgA) nephropathy, IgA vasculitis, lupus nephritis, infection-related GN {poststreptococcal, Hepatitis C Virus (HCV)}, and fibrillary GN with ...
Dhruvi Reddy, Siva Ranganthan Green, R Hemachandar   +2 more
doaj   +1 more source

Analysis of Various Types of Glomerulonephritis with Crescents at a Single Center

International Journal of Nephrology, 2022
Background. The importance of crescent formation in glomerulonephritis has increased. However, detailed analysis of crescentic glomerulonephritis in Asia is scarce.
Tomo Nakakita, Kenichi Akiyama, Kazunori Karasawa, Yoei Miyabe, Takahito Moriyama, Keiko Uchida, Kosaku Nitta   +6 more
doaj   +1 more source

Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis [PDF]

, 2015
Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to ...
AA Eddy, Arif Khwaja, B Conway, B Hinz, C Stambe, D Bokemeyer, D Bokemeyer, D Feliers, David Long, DY Rhyu, E Diaz-Flores, Faith Hannah Nutter, FY Ma, FY Ma, FY Ma, G Wolf, GA Reif, GM D'Abaco, H Fujita, H Ha, H Tamouza, HJ Anders, J Chen, John L. Haylor, JW Pippin, JY Seo, L Aoudjit, LF Allen, LL Huang, M Peake, M Sabbatini, M Zeisberg, MA Chetram, MH De Borst, N Sakai, P Moreno-Layseca, PM Lorusso, R Ohashi, R Roskoski Jr, S Omori, S Wang, S Wang, SD Oldroyd, SK Jo, SP Davies, T Ishida, T Masaki, T Wada, T Xu, W Bechtel, Y Han   +50 more
core   +8 more sources

Crescentic glomerulonephritis in children [PDF]

Pediatric Nephrology, 2020
Abstract Background To date, there is insufficient knowledge about crescentic glomerulonephritis (cGN), the most frequent immunologic cause of acute kidney injury in children. Methods Over a period of 16 years, we retrospectively analyzed kidney biopsy results, the clinical course, and laboratory data in 60 pediatric patients diagnosed with cGN ...
Ulrike Mayer, Jessica Schmitz, Jan Hinrich Bräsen, Lars Pape   +3 more
openaire   +3 more sources

Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated Glomerulonephritis

Pharmaceuticals, 2022
Crescentic glomerulonephritis is a devastating autoimmune disease that without early and properly treatment may rapidly progress to end-stage renal disease and death.
Lucia Tejedor-Santamaria, Jose Luis Morgado-Pascual, Laura Marquez-Exposito, Beatriz Suarez-Alvarez, Raul R. Rodrigues-Diez, Antonio Tejera-Muñoz, Vanessa Marchant, Sergio Mezzano, Carlos Lopez-Larrea, Anna Sola, Gema Maria Fernandez-Juarez, Alberto Ortiz, Sandra Rayego-Mateos, Marta Ruiz-Ortega   +13 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

Implications of Antiphospholipid and Antineutrophilic Cytoplasmic Antibodies in the Context of Postinfectious Glomerulonephritis. [PDF]

, 2017
While antineutrophil cytoplasmic antibody (ANCA) positivity has been documented in some patients with postinfectious glomerulonephritis (PIGN) and is associated with more severe disease, antiphospholipid antibodies (APA) are not known to be a common ...
Butani, Lavjay, Leifer, Daniel
core   +4 more sources

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R, Anders HJ, Anders HJ, Anders HJ, Bruhl H, Burne-Taney MJ, Feng L, Fituri O, Fujinaka H, Garcia GE, Grone HJ, Keane MP, Mack M, Miura M, Murphy PM, Nath KA, Perez de Lema G, Rollins BJ, Romagnani P, Segerer S, Segerer S, Segerer S, Tang WW, Taub DD, Tesch GH, Tokuda A, Topham PS, Vielhauer V, Vielhauer V, Wada T, Wang Y, Wenzel U, Wu X, Wu X, Zernecke A   +34 more
core   +1 more source