Results 1 to 10 of about 2,541 (155)

Associate toxin-antitoxin with CRISPR-Cas to kill multidrug-resistant pathogens [PDF]

open access: yesNature Communications, 2023
CreTA, CRISPR-regulated toxin-antitoxin (TA), safeguards CRISPR-Cas immune systems by inducing cell dormancy/death upon their inactivation. Here, we characterize a bacterial CreTA associating with the I-F CRISPR-Cas in Acinetobacter.
Rui Wang   +11 more
doaj   +2 more sources

Associations of characteristics of previous induced abortion with different grades of current placenta accreta spectrum disorders

open access: yesThe Journal of Maternal-Fetal & Neonatal Medicine, 2023
Objective Induced abortion could increase the risk of placenta accreta spectrum (PAS) in the next pregnancy. We aimed to explore the associations between characteristics of previous induced abortion and grades of current PAS.Methods A retrospective case ...
Rui Li   +4 more
doaj   +1 more source

Systemic Photoprotection in Skin Cancer Prevention: Knowledge among Dermatologists

open access: yesBiomolecules, 2021
Background: Systemic photoprotection (i.e., administration of substances such as nicotinamide, carotenoids, and vitamin D) may be important to reduce photocarcinogenesis or to support long-term protection against UV irradiation.
Luca Fania   +11 more
doaj   +1 more source

Similar Levels of Disease Severity Correspond to a Greater Burden of Illness in Women Compared with Men with Hidradenitis Suppurativa

open access: yesActa Dermato-Venereologica, 2023
is missing (Short communication)
Tonia Samela   +7 more
doaj   +1 more source

PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis

open access: yesCells, 2021
The phosphatidylinositol 3-kinase (PI3K)-dependent signaling pathway is aberrantly activated in psoriatic lesions and contributes to disease pathogenesis.
Laura Mercurio   +6 more
doaj   +1 more source

Basal Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches

open access: yesBiomedicines, 2020
Basal cell carcinoma (BCC) is the most common human cancer worldwide, and is a subtype of nonmelanoma skin cancer, characterized by a constantly increasing incidence due to an aging population and widespread sun exposure.
Luca Fania   +10 more
doaj   +1 more source

Conservative Surgical Management of Placenta Accreta Spectrum: A Pragmatic Approach

open access: yesJournal of Investigative Surgery, 2021
In the last 30 years, with increasing cesarean section rates, the incidence of the placenta accreta spectrum has also increased. It is estimated that by the year 2020 there will be nearly 9000 cases annually in the United States.
Joanna Sichitiu   +3 more
doaj   +1 more source

Systemic Photoprotection in Melanoma and Non-Melanoma Skin Cancer

open access: yesBiomolecules, 2023
Non-melanoma skin cancers (NMSCs), which include basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and actinic keratosis (AK), are the most common cancer diseases in the Caucasian race.
Mariafrancesca Hyeraci   +11 more
doaj   +1 more source

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