Results 61 to 70 of about 5,202 (159)
Pharmacology and Clinical Pharmacy Research, 2019 Thyroid hormone (TH) play crucial roles in the growth and development of brain. Efficiency of TH during the perinatal period results in severe mental and physical retardation, known as cretinism in humans.
Miski A. Khairinisa +6 more
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ORAL ASPECTS OF CRETINISM INCLUDING RETARDED ERUPTION : REPORT OF A CASE
, 1991 The authors report a case found as cretinism at the age of 34 years, especially on the oral and maxillofacial aspects. The patient, a female, was referred to our clinic at the age of 35 years with the complaints of prolonged retention of the deciduous ...
木南, 秀雄 +7 more
core +1 more source
Prolonged Ileus in an Infant Presenting with Primary Congenital Hypothyroidism
Case Reports in Pediatrics, 2015 Congenital hypothyroidism (CH) is the most common endocrine disorder affecting the newborn. Universal newborn screening (NBS) has virtually eliminated the static encephalopathy and devastating neurodevelopmental syndrome known as cretinism.
Caroline Chua +3 more
doaj +1 more source
Food Science &Nutrition, Volume 13, Issue 9, September 2025.This study investigated the association between urinary iodine concentration and cognitive function in older adults using NHANES 2011–2014 data. Our study found that iodine deficiency (UIC < 100 μg/L) was associated with a significantly reduced risk of cognitive decline compared to the adequate iodine intake group (UIC 100–199 μg/L) (adjusted OR = 0.54,
Zeyong Sun +6 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.T3 loss in congenital hypothyroidism (CH) downregulates TRPC6 in dentate granule cells (DGCs), which reduces dendritic spine density via the CaMKIV/CREB signaling pathway. TRPC6 agonist hyperforin rescues DGCs' dendritic spines and cognitive function of CH pups.
Tianci Li +10 more
wiley +1 more source
PLoS ONE, 2013 The origin of hominins found on the remote Indonesian island of Flores remains highly contentious. These specimens may represent a new hominin species, Homo floresiensis, descended from a local population of Homo erectus or from an earlier (pre-H ...
Karen L Baab +2 more
doaj +1 more source
PEGASUS: Prediction of MD‐derived protein flexibility from sequence
Protein Science, Volume 34, Issue 8, August 2025.Abstract Protein flexibility is essential to its biological function. However, experimental methods for its assessment, such as X‐ray crystallography and nuclear magnetic resonance spectroscopy, are often limited by experimental variability and high cost, leading to a gap between the number of identified protein sequences and the available experimental
Yann Vander Meersche +5 more
wiley +1 more source
Clinical picture of endemic cretinism in central Apennines (Montefeltro).
, 1992 Endemic cretinism is still present in an endemic goiter area of the central Apennines (Montefeltro) (goiter prevalence 55%; mean urinary iodine level 39 micrograms/g creatinine). Clinical and biochemical features of patients with myxedematous, neurologic,
Andreani M +9 more
core
Reversibility of severe hypothyroidism with supplementary iodine in patients with endemic cretinism.
, 1986 The reversibility of thyroid dysfunction in children with endemic cretinism treated with supplemental iodine is unknown. To study this question we conducted a five-month follow-up of 51 patients with cretinism (age 14 and below), who were randomly ...
François Delange +19 more
core +1 more source
Health Consequences of Iodine Deficiency
Sultan Qaboos University Medical Journal, 2007 Iodine Deficiency Disorders (IDD) are one of the biggest worldwide public health problem of today. Their effect is hidden and profoundly affects the quality of human life.
Umesh Kapil
doaj