Results 101 to 110 of about 26,898 (212)
MRI and clinical syndrome in dura materrelated Creutzfeldt-Jakob disease [PDF]
, 2018 Objective : Iatrogenic Creutzfeldt-Jakob disease (iCJD) is mainly associated with dura mater (DM) grafts and administration of human growth hormones (hGH). Data on disease course in DM-CJD are limited.
Barsic, B. +12 more
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Prion disease: experimental models and reality [PDF]
, 2017 The understanding of the pathogenesis and mechanisms of diseases requires a multidisciplinary approach, involving clinical observation, correlation to pathological processes, and modelling of disease mechanisms.
Brandner, S, Jaunmuktane, Z
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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
Acta Neuropathologica Communications, 2019 For the transmissible, neurogenerative family of prion diseases, few human models of infection exist and none represent structured neuronal tissue. Human cerebral organoids are self-organizing, three-dimensional brain tissues that can be grown from ...
Bradley R. Groveman +6 more
doaj +1 more source
Cross currents in protein misfolding disorders: interactions and therapy. [PDF]
, 2009 Protein Misfolding Disorders (PMDs) are a group of diseases characterized by the accumulation of abnormally folded proteins. Despite the wide range of proteins and tissues involved, PMDs share similar molecular and pathogenic mechanisms.
Green, Kristi M +2 more
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Sporadic cjd and retinitis punctata albescansa case report and literature review [PDF]
, 2014 Introduction Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common form of CJD causing 85% of all cases. Various phenotypes of sCJD have been identified including Heidenhain variant which has early and predominant visual symptoms with most ...
Hanif Khan, Yusra, Khan, Quratulain
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BMC GeriatricsWe report an atypical case of Creutzfeldt-Jakob Disease (CJD) mimicking Frontotemporal Dementia (FTD) in a 68-year-old male. The patient initially presented with an anxious-depressive syndrome, progressing over 29 months to include dysexecutive syndrome,
Carlo Manco +6 more
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Gene expression profiling en association with prion-related lesions in the medulla oblongata of symptomatic natural scrapie animals. [PDF]
, 2011 The pathogenesis of natural scrapie and other prion diseases remains unclear. Examining transcriptome variations in infected versus control animals may highlight new genes potentially involved in some of the molecular mechanisms of prion-induced ...
Acín, Cristina +10 more
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Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes [PDF]
, 1986 Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles.
Blatt, Cila +13 more
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Neurobiology of Disease, 2014 Prion diseases are progressive disorders that affect the central nervous system leading to memory loss, personality changes, ataxia and neurodegeneration.
A. Murali, R.A. Maue, P.J. Dolph
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