Results 51 to 60 of about 11,403 (205)

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1650-1661, June 2026.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Some evidences about Crimean Congo Hemorrhagic Fever [PDF]

, 2008
[No abstract ...
Abbasi, A., Besharat, S., Jabbari, A.
core  

Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]

, 2013
Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl, Anne-Lie Blomström, Delhaye, Dunn, Esther Schnettler, Geerts-Dimitriadou, Hampsey, Isabelle Dietrich, Kakach, Lanciotti, Nagata, Saleh Eifan, Storms, Verbruggen, Wijkamp, Yadani, Ye, Zhao   +17 more
core   +3 more sources

Tick‐Tac‐Foe: When Ticks, Trade, and Zoonotic Pathogens Align in African Wet Meat Markets

Public Health Challenges, Volume 5, Issue 2, June 2026.
ABSTRACT Zoonotic diseases account for over ∼60% of infectious diseases and present a significantly growing fatality threat in Africa. Live and wet markets (LWMs) in Africa function as key economic venues that support human livelihoods through social interaction and trade in food stuff, including meat and other animal‐based products.
Allen Takudzwa Munaro
wiley   +1 more source

Crimean-Congo Haemorrhagic Fever in Kosova : a fatal case report

Virology Journal, 2006
Crimean-Congo haemorrhagic fever (CCHF) is an often fatal viral infection described in about 30 countries around the world. The authors report a fatal case of Crimean-Congo hemorrhagic fever (CCHF) observed in a patient from Kosova. The diagnosis of CCHF
Raka Lul, Ahmeti Salih
doaj   +1 more source

Response to the Letter: Mean Platelet Volume to Platelet Count Value May Not Be a Prognostic Marker in Patients with Crimean–Congo Hemorrhagic Fever

Rambam Maimonides Medical Journal, 2020
We carefully read the comments of our respected colleagues Cengiz Beyan and Esin Beyan regarding our article, “An Evaluation of the Different Serum Markers Associated with Mortality in Crimean–Congo Hemorrhagic Fever.”1 We actually investigated many ...
Yusuf Kenan Tekin, Aynur Engin
doaj   +1 more source

Risk Factors for Tick‐Borne Diseases in Germany: A Scoping Review

Zoonoses and Public Health, Volume 73, Issue 4, Page 297-313, June 2026.
ABSTRACT Tick‐borne diseases (TBDs) have proliferated in Germany. The two most prevalent TBDs, Lyme‐borreliosis and tick‐borne encephalitis, can present with nonspecific symptoms and lead to serious neurological complications. To date, a review synthesising the risk factors of acquiring a TBD in Germany is missing.
Carolin Schlupp, Matthias Hans Belau
wiley   +1 more source

Interactions of Human Dermal Dendritic Cells and Langerhans Cells Treated with Hyalomma Tick Saliva with Crimean-Congo Hemorrhagic Fever Virus

Viruses, 2018
Crimean-Congo hemorrhagic fever virus is one the most important and wide spread tick-borne viruses. Very little is known about the transmission from the tick and the early aspects of pathogenesis.
Sergio E. Rodriguez, Alexander J. McAuley, Aysen Gargili, Dennis A. Bente   +3 more
doaj   +1 more source

Potential entry pathways for 25 vector‐borne disease agents

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This Scientific Report identifies the potential entry pathways for 25 selected vector‐borne diseases (VBDs) into currently free EU Member States. The diseases comprise 12 listed under the Animal Health Law (AHL) and 13 non‐listed diseases, selected using predefined eligibility criteria.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Knowledge mapping of risk mitigation measures against vector‐borne diseases

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract A comprehensive synthesis of current evidence on surveillance, prevention and control measures for 25 selected vector‐borne diseases (VBDs) affecting animals in the EU is presented here. The assessment integrates evidence from systematic literature reviews, modelling studies, field investigations and expert judgement.
European Food Safety Authority (EFSA), Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Sofie Dhollander, Stefania Tampach, Jordi Figuerola, Hans Hermann Thulke, Miguel Ángel Chueca Miranda   +8 more
wiley   +1 more source