Results 181 to 190 of about 3,214,730 (354)

Human phase‐I metabolism of three synthetic cannabinoids bearing a cumyl moiety and a cyclobutyl methyl or norbornyl methyl tail: Cumyl‐CBMEGACLONE, Cumyl‐NBMEGACLONE, and Cumyl‐NBMINACA

open access: yesDrug Testing and Analysis, EarlyView.
The human phase‐I metabolism of three SCRAs bearing a cumyl moiety and a CBM or NBM tail, based on LC‐qToF‐MS data of authentic urine specimens. Abstract Synthetic cannabinoid receptor agonists (SCRAs) continue to show high prevalence on the new psychoactive substances drug market.
Arianna Giorgetti   +6 more
wiley   +1 more source

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA

open access: yesDrug Testing and Analysis, EarlyView.
Another Chinese generic ban‐evading SCRA, CH‐FUBBMPDORA, has emerged. This study reports its first identification in Europe, its analytical characterization (NMR, Raman, FTIR, GC–MS, and HRMS), its cannabinoid activation potential in a βarr2 recruitment assay, and its metabolization profile.
Marie H. Deventer   +13 more
wiley   +1 more source

Characterising a New Cannabis Trend: Extensive Analysis of Semi‐Synthetic Cannabinoid‐Containing Seizures From Germany

open access: yesDrug Testing and Analysis, EarlyView.
A LC–MS/MS method has been validated for analysis of semi‐synthetic cannabinoids (SSC) and selected phytocannabinoids in seizures. Further SSC‐derivatives were implemented into the method for qualitative detection. The methodology was applied to a sample collective (n = 80) including cannabis flowers, resins, edibles and vape liquids.
Marica Hundertmark   +4 more
wiley   +1 more source

Is Policy Coherence Leaving No One Behind? Analyzing Gender Inequality in the Governance of the Sustainable Development Goals in India

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT The pledge to Leave No One Behind is central to the 2030 Agenda and cuts across all the Sustainable Development Goals (SDGs). To realize this cross‐sectoral approach to inequality, policy coherence is considered an important tool. This article questions whether and how policy coherence leaves no one behind.
Nikki J. J. Theeuwes   +2 more
wiley   +1 more source

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