Results 81 to 90 of about 1,168,879 (292)

Financial Crises In Spain: Lessons From The Last 150 Years [PDF]

The financial disturbances that originated in the US in the second half of 2007 are the latest in a series of episodes in various regions of the world in recent years.
Concha Betrán, María Angeles Pons, Pablo Martín-Aceña   +2 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Features of using anti-crisis potential in anti-crisis management for overcoming crises in the enterprise

Вісник Житомирського державного технологічного університету: Серія: економіка, управління та адміністрування, 2019
The subject of the research is the anti-crisis potential of the enterprise. The purpose of the work is to investigate the peculiarities of using anti-crisis management of anti-crisis potential to overcome various types of crises in the enterprise.
O.A. Shatailo
doaj   +1 more source

Crises rhétoriques, crises démocratiques [PDF]

Questions de communication, 2007
Parmi les travaux contemporains qui portent sur la rhetorique et l’argumentation, plusieurs tendances sont a observer Ainsi en est-il de celles qui analysent la bonne conduite d’un debat a partir d’un modele idealise compose d’un ensemble de regles que les participants seraient tenus de respecter On reconnait la l’inspiration anglo-saxonne dont l’ecole
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Le faux miroir de l’objectif : enquête sur la fabrication des données spatiales

L'Espace Politique
The following article deals with the production of spatial data by using drones and satellites with a particular emphasis on the civil and humanitarian sphere. Though different spaces are explored, the investigation mainly focuses on the Syrian territory
Marvin Freyne
doaj   +1 more source

Violence: The church is part of the problem

Verbum et Ecclesia, 2011
South African Christians are not only surrounded by violence, but actively participate in acts of violence, therefore contributing to the unacceptably high levels of anxiety and counterviolence across the country.
Erna Oliver
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source