Results 111 to 120 of about 1,213,615 (254)
Zombie firms and resource allocation: research trends and developments during the spread of COVID-19
Journal of Applied EconomicsWe identify so-called “zombie firms,” which survive with banks’ and governments’ support despite performing poorly without the prospect of recovery, using firms’ financial data.
Kotone Yamada +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Conceptualizing Cross-Border Crises: the Specificity of Ukrainian-Polish Crisis Communications
Медіафорум: аналітика, прогнози, інформаційний менеджментCrises of a cross-border nature are positioned as a critically important domain not only of national but also of international politics. Threats not recognizing national borders constitute the main challenge in cross-border crises and require not only ...
Yevheniia Tykhomyrova
doaj +1 more source
Crises and Sudden Stops: Evidence from International Bond and Syndicated-Loan Markets [PDF]
The crises in Mexico, Thailand, and Russia in the 1990s spread quite rapidly to countries as far apart as South Africa and Pakistan. In the aftermath of these crises, many emerging economies lost access to international capital markets.
Graciela L. Kaminsky
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Currency Crises: Is Central America Different? [PDF]
In a recent paper we analyzed the determinants of currency crises in a sample of 30 high and middle income countries (Esquivel and Larraín, 1998). In this work we focus on Central America and analyze whether the determinants of currency crises in this ...
Felipe Larraín, Gerardo Esquivel
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Cluster Analysis of the Impact of Currency Regime Type on Features of the Spread of Financial Crises
Operations Research and Decisions, 2018 The paper presents the results of research on the impact of currency regime type on features of the spread of financial crises. The focus is on constructing a neural network to identify groups of countries exhibiting similar behaviour in the dynamics of ...
Inna Strelchenko
doaj
Banking Crises and the Lender of Last Resort: How crucial is the role of information? [PDF]
This article develops a model of bank runs and crises and analyses how the presence of a lender of last resort (LOLR) affects the solvency of the banking system.
Hassan Naqvi
core