Results 101 to 110 of about 4,296,035 (305)
The monetary mechanics of the crisis [PDF]
In response to the financial and economic crisis, central banks, unlike in the 1930s, have created enormous amounts of money. There are fears that this will lead to inflation, but it is base money (the central bank's liabilities) that has expanded; total
Jürgen von Hagen
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Crisis? What crisis? Australia after(?) the economic crisis [PDF]
The global economic crisis is not over for Australia. Instead, its effects have been delayed rather than avoided. China’s economic stimulus delayed the impact of the crisis, but as Chinese economy rebalances and its growth slows, Australian policy-makers
Tom Conley
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Humanities & Social Sciences CommunicationsPrevious research has examined how motivational goals influence decision-making in advertising for both older and younger adults, and the findings support the proposal of socioemotional selective theory (SST), which suggests that older adults pursue ...
Wanying Chen +5 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Bank Lending and Contagion: Evidence from the Asian Crisis [PDF]
, 2001 This paper analyzes how the crisis in Asia spread during the second half of 1997. We cast our net wide and investigate several possible trade and financial linkages among the Asian economies.
Kaminsky, Graciela, Reinhart, Carmen
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Hamlet’s crisis of meaning, mental wellbeing and meaninglessness in the War on Terror [PDF]
, 2008 Drawing on Shakespeare, and in particular Hamlet's psychological crisis, this paper examines the relationship between emotions and meaning, a key theme in artistic work, but, it is argued, neglected in social psychology.
Pupavac, Vanessa
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source