Results 41 to 50 of about 771,765 (294)
Introducing green logistics elements into a selected company - case study [PDF]
In the case study, we examine the economic impacts of the environmental repercussions of logistics in the selected company. We deal with the current environmental and financial demands of the company chosen fleet and propose the adequate replacement of ...
Tomastik Marek+3 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Sanitary Crisis, Civilizational Crisis [PDF]
Sanitary Crisis, Civilizational Crisis is the translation of Michel Maffesoli’s Crise sanitaire, crise civilisationnelle. This paper can be taken as his pronouncement on the civilizational crisis that the COVID-19 pandemic acutely reveals. Maffesoli’s text urges one to see beyond secondary causes or dramatic representations of the pandemic as a ...
openaire +3 more sources
Trade Crisis? What Trade Crisis? [PDF]
We investigate the 2008–2009 trade collapse using microdata from a small open economy, Belgium. Belgian exports and imports mostly fell because of smaller quantities sold and unit prices charged rather than fewer firms, trading partners, and products being involved in trade.
Behrens, K, Corcos, G, Mion, G
openaire +11 more sources
Depression, anxiety, PTSD, and OCD after stillbirth: a systematic review
Background This systematic review aimed to provide an updated summary of studies investigating depression, anxiety, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder (OCD) in parents after stillbirth (from 20 weeks gestational age ...
Cèline Lossius Westby+4 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Fire Losses in the Slovak Republic - Their Classification and Quantification
The paper deals with approaches to fire loss classification and quantification. Direct and indirect loss, total loss per fire and the relation of direct and indirect loss to the gross domestic product (GDP) are calculated.
Jozef Klucka+2 more
doaj +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source