Results 71 to 80 of about 4,257,137 (288)

Do economic crises lead to health and nutrition behavior responses?: analysis using longitudinal data from Russia [PDF]

open access: yes, 2013
Using longitudinal data on more than 2,000 Russian families spanning the period between 2007 and 2010, this paper estimates the impact of the 2009 global financial crisis on food expenditures, health care expenditures, and doctor visits in Russia.
Ajwad, Mohamed Ihsan   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Sanctions and Embargoes as a Crisis Response Instrument in the Context of the Ukrainian Crisis

open access: yesCommunications, 2015
The paper analyzes the importance of sanctions and embargoes as a tool used by organizations of international crisis management to resolve large-scale crisis events in a peaceful way.
Veronika Orieskova, Jan Havko
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Emerging Global Health Crisis of Our Times- Climate Change [PDF]

open access: yes, 2020
The progress of the human race over the last 200 years is unprecedented in recent history. Rapid industrialization, urbanization, and consumerism have made lives easier for humankind. Still, these changes come at a very high price.
Anwer, A. (Ammar)
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Crisis: what crisis? [PDF]

open access: yesEuropean Spine Journal, 1998
There is a large economic cost associated with low back pain. In 1994 its cost to the United Kingdom (UK) was estimated by the UK Clinical Standards Advisory Group report to be nearly pound sterling 6,000 million (ECU 8,350 million) annually. This principally consists of the indirect costs of lost production and disability payments rather than direct ...
openaire   +2 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Sexual orientation differences in treatment expectation, alliance, and outcome among patients at risk for suicide in a public psychiatric hospital

open access: yesBMC Psychiatry, 2017
Background Sexual minority (SM) individuals (gay, lesbian, bisexual, or otherwise nonheterosexual) are at increased risk for mental disorders and suicide and adequate mental healthcare may be life-saving.
Martin Plöderl   +5 more
doaj   +1 more source

Crisis Management [PDF]

open access: yes, 2019
[Excerpt] It’s no longer a matter of WHETHER a crisis will happen or not, it’s a matter of WHAT TYPE it is and WHEN it occurs. An organization (and its union) that can manage and recover from a crisis demonstrates competence – the results can mean ...
Brown, Nellie J
core   +1 more source

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