Results 71 to 80 of about 4,296,035 (305)

ESSENCE AND COMPONENTS OF INNOVATION POTENTIAL IN THE SYSTEM OF CRISIS MANAGEMENT

Модернизация, инновация, развитие, 2015
The article specifies the concept and composition of innovation potential and off ers the structure of this economic category. The concept of the innovation potential of the company is considered.
N. G. Akulova, A. S. Urusov
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

“Life gives you a lemon, you make lemonade”: a qualitative study of identity among young male adult cancer survivors

Journal of Cancer Research and Clinical Oncology
Purpose This study aimed to explore how male young adult cancer survivors (YACSs), aged 18–39, reconstruct and make sense of their identity following the completion of cancer treatment by answering the research question: “How do male YACS perceive and ...
Glenn F. Flecther, May Aa. Hauken
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Sanctions and Embargoes as a Crisis Response Instrument in the Context of the Ukrainian Crisis

Communications, 2015
The paper analyzes the importance of sanctions and embargoes as a tool used by organizations of international crisis management to resolve large-scale crisis events in a peaceful way.
Veronika Orieskova, Jan Havko
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Crisis: what crisis? [PDF]

European Spine Journal, 1998
There is a large economic cost associated with low back pain. In 1994 its cost to the United Kingdom (UK) was estimated by the UK Clinical Standards Advisory Group report to be nearly pound sterling 6,000 million (ECU 8,350 million) annually. This principally consists of the indirect costs of lost production and disability payments rather than direct ...
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Norwegian traumatic grief inventory-self report plus (TGI-SR+): a psychometric evaluation in traumatically bereaved people

European Journal of Psychotraumatology
Background: Prolonged grief disorder (PGD) has been added to the ICD-11 and DSM-5-TR. The Traumatic Grief Inventory-Self Report Plus (TGI-SR+) assesses self-rated PGD intensity as defined in ICD-11 and DSM-5-TR.
Lonneke I. M. Lenferink, Iren Johnsen, Pål Kristensen, Nataskja-Elena Kersting Lie, Josefin Sveen   +4 more
doaj   +1 more source