Results 51 to 60 of about 3,275,688 (215)

Heterogeneous profiles of virtue personality trait in anxiety-depression symptom networks and simulated intervention effects: evidence from a large college student sample

open access: yesBMC Psychology
Background Anxiety and depression frequently co-occur among college students, yet their symptom-level connections may vary across person-level characteristics.
Yuxin Zhang   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Intervention effects and mechanisms of online single session therapy on test anxiety in university students: A randomized controlled trial

open access: yesInternet Interventions
Objective: This study aimed to develop an online Single-Session Therapy (SST) intervention program for test anxiety and explore the intervention effects and mechanisms underlying the effectiveness of this SST program for university students experiencing ...
Liying Chen   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Positive resonance: Successful interpersonal emotion regulation facilitated relationship closeness by enhanced inter-brain synchronization

open access: yesNeuroImage
Interpersonal emotion regulation (IER) refers to the dynamic process where a regulator employs specific strategies to alleviate a target's distress. It remains unclear whether successful IER could facilitate interpersonal relationship closeness (IRC ...
Tongtong Zhu   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Victim impact statements / reports: a guide for victim supporters from Rape Crisis Network Ireland [PDF]

open access: yes, 2011
Funded by the Commission for the Support of Victims of ...
Rape Crisis Network Ireland
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Relationship power attenuated the effects of gratitude on perceived partner responsiveness and satisfaction in romantic relationships

open access: yesScientific Reports
There is a gap in whether relationship power affects the association between gratitude and relationship satisfaction in romantic relationships. Based on the relationship maintenance model and the social distance theory of power, the present study adopted
Luyao Jin, Tongtong Zhu, Yanmei Wang
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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