Results 111 to 120 of about 603,016 (278)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Assessing Greece’s social vulnerability patterns in times of perma-crisis (2008–2022)
Frontiers in Political ScienceIntroductionThe study aims to map and analyse the development of social vulnerability patterns in Greece through a perma-crisis context (economic crisis, austerity, covid-19, energy, and inflation crisis) over the period 2008-2022.MethodsThe paper rests ...
Michail Melidis +2 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Application of EREP imagery to fracture-related mine safety hazards and environmental problems in mining [PDF]
The author has identified the following significant results. All Skylab 2 imagery received to date has been analyzed manually and data related to fracture analysis and mined land inventories has been summarized on map-overlays.
Amato, R. V. +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The 2008 rice crisis: shock and new challenges [PDF]
, 2011 West Africa currently imports 5.2 million tonnes of rice, compared with 1.7 million tonnes in the early 1990s, and is only able to cover 60% of its needs despite possessing considerable rice-growing potential.
CILSS - MLI +4 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The global economic crisis and repositioning the influencing centres [PDF]
The global economic crisis is influencing many areas: scientific research, social, politics. The crisis is generating new economic models, new social models – individually and collectively and also a new influencing centres map. The opportunity of crisis
Pricop Oliver Constantin +1 more
core
Working towards an Improved Monitoring Infrastructure to support Disaster Management, Humanitarian Relief and Civil Security [PDF]
, 2005 Within this paper experiences and results from the work in the context of the European Initiative on Global Monitoring for Environment and Security (GMES) as they were gathered within the German Remote Sensing Data Center (DFD) are reported.
Kemper, Thomas +3 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source