Results 241 to 250 of about 270,386 (291)

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

The multidimensional social ecological needs and service utilization patterns of youth using non-medical prescription opioids: an observational study of routinely collected data in a provincial integrated youth services initiative. [PDF]

Subst Abuse Treat Prev Policy
Marchand K, Liu G, Hastings KG, Palis H, Mathias S, Sutherland JM, Barbic S.   +6 more
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Traditional, complementary and integrative health within universal systems: a transdisciplinary integrative approach to chronic conditions in the Brazilian SUS. [PDF]

Front Public Health
Cohrs FM, Bignardi FAC.
europepmc   +1 more source

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity

Advanced Science, EarlyView.
This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao, Lisa‐Marie Skrip, Heiko Tzschätzsch, Tom Meyer, Hossein S. Aghamiry, Alexander Arnold, Lene Änne Böhne, Jakob Jordan, Oliver Boehm, Agnes K. Boehm, Steffen Görner, Jakob Schattenfroh, Yanglei Wu, Pedro Augusto Dantas de Moraes, Johann Pratschke, Jürgen Braun, Igor M. Sauer, Jing Guo, Ingolf Sack, Karl H. Hillebrandt   +19 more
wiley   +1 more source

Development and validation of the concise midlife crisis measure. [PDF]

Sci Rep
Husain W, Trabelsi K, Ali A, Usman Y, Husain MA, Ijaz F, Ammar A, Jahrami H.   +7 more
europepmc   +1 more source

Combating Antimicrobial Resistance in Africa: A Call for Multidimensional Strategies to a Growing Crisis.

Ethiopian journal of health sciences
Gudina, Esayas Kebede, Gashaw, Mulatu, Tufa, Tafese Beyene   +2 more
openaire   +2 more sources

How genetic counselors in North America describe their professional identity. [PDF]

J Genet Couns
Schwartz L, Stenberg K, Casey A, Fitzpatrick J, Mackall MS, Goodenberger ML, Arjunan A, Witherington S, Kalia I, Mills R.   +9 more
europepmc   +1 more source

[Planetary health: The inescapable role of family medicine]. [PDF]

Aten Primaria
Galindo Ortega G, Del Campo Giménez M, Gutiérrez Muñoz B, Navarro Beltrá M, Almécija Pérez MC.   +4 more
europepmc   +1 more source