Results 41 to 50 of about 1,559,038 (329)
Maldives crisis: a catch-22 situation for India [PDF]
, 2018 The current crisis in the Maldives can be seen as an opportunity for India to regain its lost influence in the country, and subsequently in the region.
Sharma, Sarral
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
An Innovative Method for Supplying Water for Consumption in Crisis Situations [PDF]
Bezpieczeństwo i Technika Pożarnicza, 2018 Aim: Preliminary application for a utility model entitled „Temporary mobile station for the treatment of water for consumption”, particularly useful in emer-gency situations, such as floods, when both surface and deep water is contaminated.
Sławczo Denczew
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Hungary and the eurozone crisis: a comedy of errors? [PDF]
, 2012 The spill-over of the global fi nancial crisis has uncovered the weaknesses in the governance of the EMU. As one of the most open economies in Europe, Hungary has suff ered from the ups and downs of the global and European crisis and its mismanagement ...
Csaba, László
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Third European Quality of Life Survey – Quality of Life in Europe: Families in the Economic Crisis [PDF]
, 2013 [Excerpt] The European Quality of Life Survey (EQLS) provides a reliable picture of the living conditions and the social situation of Europeans before and during the economic crisis. But how has the crisis affected families with children?
Ahrendt, Daphne +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Topic Jerk Detector: Detection of Tweet Bursts Related to the Fukushima Daiichi Nuclear Disaster
Information, 2020 In recent disaster situations, social media platforms, such as Twitter, played a major role in information sharing and widespread communication. These situations require efficient information sharing; therefore, it is important to understand the trends ...
Hiroshi Nagaya +3 more
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source