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The CRISPR-Cas system in molecular diagnostics

Clinica Chimica Acta
Robust, sensitive, and rapid molecular detection tools are essential prerequisites for disease diagnosis and epidemiological control. However, the current mainstream tests necessitate expensive equipment and specialized operators, impeding the advancement of molecular diagnostics. The CRISPR-Cas system is an integral component of the bacterial adaptive
Rao, Song, Zhongyi, Chen, Hongtao, Xiao, Haojun, Wang   +3 more
openaire   +2 more sources

Advances in CRISPR-Cas systems for epigenetics

The CRISPR-Cas9 method has revolutionized the gene editing. Epigenetic changes, including DNA methylation, RNA modification, and changes in histone proteins, have been intensively studied and found to play a key role in the pathogenesis of human diseases.
Mahnoor, Ilyas, Qasim, Shah, Alvina, Gul, Huzaifa, Ibrahim, Rania, Fatima, Mustafeez Mujtaba, Babar, Jayakumar, Rajadas   +6 more
openaire   +2 more sources

The CRISPR/Cas system in zebrafish

2020
De Santis, Flavia, Terriente, Javier, Di Donato, Vincenzo   +2 more
openaire   +1 more source

Editing and investigating genomes with TALE and CRISPR/Cas systems: Applications of artificial TALE and CRISPR–Cas systems

Methods, 2014
Carine Giovannangeli, Jean-Paul Concordet   +1 more
openaire   +3 more sources