A prospective natural history study protocol for clinical trial readiness in synaptic disorders
Abstract Objective STXBP1‐related disorder (STXBP1‐RD) and SYNGAP1‐related disorder (SYNGAP1‐RD) are two common genetic synaptopathies that are associated with epilepsy, developmental delay, intellectual developmental disorder, and behavioral problems.
Jillian L. McKee +38 more
wiley +1 more source
The concept of vulnerability and its relation to equality in the context of human rights: cases from climate change, anti-discrimination and asylum. [PDF]
Mayrhofer M, Ammer M, Wladasch K.
europepmc +1 more source
Abstract Pediatric drug‐resistant epilepsy (DRE) remains a significant clinical challenge, with few effective pharmacological options. This European multicenter retrospective study assessed the real‐world efficacy, tolerability, and retention of off‐label cenobamate (CNB) in 108 children and adolescents with DRE (median age: 13.83 years, range 3.9–19.8)
Konstantin L. Makridis +14 more
wiley +1 more source
Stewardship opportunities in peripartum infections: a review of quality improvement initiatives and future directions. [PDF]
Bailey P +9 more
europepmc +1 more source
Abstract Research Summary The rise of emerging market lead firms (LFs) in global value chains (GVCs) challenges the prevailing view that only multinational corporations (MNCs) from advanced economies lead systems integration, design, and innovation activities.
Yuanyuan Wu, Paola Perez‐Aleman
wiley +1 more source
The Politics of Interdictive Jurisprudence: Interrogative Practices and Psychological Evaluations (Gemütszustandsuntersuchungen) in the Adjudication of Civil Interdiction Cases before Berlin's District Courts (1877-1914). [PDF]
Engstrom EJ.
europepmc +1 more source
Abstract Research Summary Trade wars increasingly manifest in the contemporary environment for global business; thereby, calling for examination of MNE strategic responses. MNEs can respond to such shocks by leveraging their strategic flexibility and engaging in retrenchment and redeployment; that is, the respective scaling down (up) of subsidiary ...
Hyewon Ma, Joseph A. Clougherty
wiley +1 more source
Best practices of judicial governance: A scoping review protocol. [PDF]
Chaves LVR +5 more
europepmc +1 more source
ABSTRACT This paper explores the perspectives of mental health and substance use providers who supported people released from custody during the pandemic in Ontario, Canada, with a focus on service disruptions, adaptations, and experiences. We conducted 20 in‐depth qualitative interviews and analysed these using Applied Thematic Analysis.
Lucas M. Seuren +6 more
wiley +1 more source
Barriers to the Implementation of Iran's Clean Air Act: A Policy-Oriented Scoping Review. [PDF]
Bouzarjomehri H +7 more
europepmc +1 more source

