Results 231 to 240 of about 460,176 (332)

RL-PMO: A Reinforcement Learning-Based Optimization Algorithm for Parallel SFC Migration. [PDF]

Sensors (Basel)
Hu H, Liu Z, Wu F.
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Solving robotics tasks with prior demonstration via exploration-efficient deep reinforcement learning. [PDF]

Front Robot AI
Shen C, Sloth C.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Secure and energy-efficient transmission in UAV-assisted intelligent reflecting surface networks. [PDF]

Sci Rep
Xue J, Xu J, Guan X, Zhang H, Gan Y.
europepmc   +1 more source

Actor-critic reinforcement learning for the feedback control of a swinging chain

, 2018
Christian Dengler, Boris Lohmann
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Experience-based integral reinforcement learning consensus for unknown multi-agent systems. [PDF]

Sci Rep
Ma L, Zhao H, Chen Y, Gao Y, Yu H.
europepmc   +1 more source

Critics of computationalism and semantic aspects of phenomenal consciousness

, 2016
Pavel N. Baryshnikov
openalex   +1 more source

Bugged (Critics, Criticism and Critical Categories)

Critical Stages, 2020
openaire   +1 more source