Results 51 to 60 of about 19,175 (267)

Creative vs Defective: A Critical Review of Malang Creative Center (MCC) in Malang City

RUAS
The Malang Creative Center (MCC) construction is a step taken by the Malang City government to support the flow of modernization and as a forum for Malang residents to develop their creativity. The MCC display concept is planned by combining the shape of
Bunga Pasadena Ineru, Yusfan Adeputera Yusran, Joko Triwinarto Santoso, Moch. Ardiansyah Fendy Wijaya, Susilo Kusdiwanggo   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Strategy Selection for Natural Resource Conservation Capturing Vagueness through Integrated Neutrosophic CRITIC-MAIRCA Approach [PDF]

Neutrosophic Sets and Systems
Conservation of natural resources like water, soil, and biodiversity is necessary for ecological balance and human survival. This article aims to identify potential ways to conserve natural resources while maintaining a balance between ecology and human ...
Bahnishikha Roy Muhuri, Florentin Smarandache, M.K. Mondal, G.S. Mahapatra, B.S. Mahapatra   +4 more
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Optimizing Blockchain Platform Selection: A Decision-Making Approach Using LLMs, Type-2 Neutrosophic Numbers, CRITIC, and MAIRCA [PDF]

Neutrosophic Sets and Systems
Blockchain (BC) platforms integrated with Generative AI (GenAI) like Large Language Models (LLMs) are the basic infrastructure for significant consumer data like Bitcoin and Smart Contracts systems, addressing challenges such as protection from anomalous
Hend Ahmed, Abduallah Gamal, Ahmed Abdelmouty   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

¿Más participación igual a mejor democracia? Acerca de la crítica a la democracia participativa // More participation equal than better democracy? On critic to participatory democracy.

Revista de Derecho Político, 2015
Resumen, En el presente, y en países como España, la crítica a la democracia representativa tal y como ésta se concibe actualmente parece ir más allá de la recurrente reflexión sobre la crisis de la representación para alcanzar niveles de enmienda a la ...
Alfredo Ramírez Nárdiz
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source