Results 81 to 90 of about 460,176 (332)
Friends, Foes, and Nel Noddings on Liberal Education
The author analyzes the debate over liberal education, focusing on critic Nel Noddings, who advocates alternative education. The author cites Noddings\u27 article Conversation as Moral Education, where Noddings identifies traditional education as ...
DeNicola, Daniel R.
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Critics have always been interested in Nathaniel Hawthorne’s literary oeuvre but that interest has varied over different periods of time. Nevertheless, we can claim that his books have always enjoyed a rousing reception.
Saša Simović, Marija Mijušković
doaj +1 more source
DAC: The Double Actor-Critic Architecture for Learning Options
We reformulate the option framework as two parallel augmented MDPs. Under this novel formulation, all policy optimization algorithms can be used off the shelf to learn intra-option policies, option termination conditions, and a master policy over options.
Whiteson, Shimon, Zhang, Shangtong
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Зинаида Гиппиус о Чехове-драматурге
Zinaida Gippius about Checkov as a playwright Z. Gippius pays more attention to the dramaturgy of Checkov of the Artistic Theatre than other playwrights or theatres. The ideal theatre for Z.
Tadeusz Osuch
doaj

